id: Pfam:PF19631
pfam_id: PF19631
name: Trypsin-co-occurring domain 2
short_name: Trypco2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19631
counters:
  proteins: 1203
  matches: 1208
  proteomes: 901
  taxa: 1361
  structures: 0
  alphafold_models: 563
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR045608
description: Trypsin-like peptidase effector in the classical NTP-dependent ternary system (vWA-MoxR-VMAP)
  frequently co-occurs with one of two proteins (Trypco1 or Trypco2) which are mostly mutually exclusively
  [[cite:PUB00098776]]. This entry also includes a member of a biosynthetic gene cluster (BGC). This BGC
  (BGC0000949) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal
  peptide). It includes a member from the A-500359 A biosynthetic gene cluster from Streptomyces griseus
  and appears to be predominantly found in bacteria [[cite:PUB00098866]].