id: Pfam:PF19929
pfam_id: PF19929
name: Immunity protein CdiI
short_name: CdiI_5
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19929
counters:
  proteins: 579
  matches: 580
  proteomes: 344
  taxa: 850
  structures: 0
  alphafold_models: 368
  domain_architectures: 9
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR045657
description: This family includes immunity protein CdiI from Erwinia chrysanthemi and related sequences,
  predominantly from gammaproteobacteria. It is an immunity protein component of a toxin-immunity protein
  module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules
  allow bacteria to communicate with and inhibit the growth of closely related neighbouring bacteria in
  a contact-dependent fashion. It protects cells against the DNase activity of CdiA, its cognate toxin
  protein, but not against non-cognate CdiA from E.coli strain 536/UPEC. Immunity protein CdiI is species-specific
  [[cite:PUB00057480]].