id: Pfam:PF20126
pfam_id: PF20126
name: Toxin TumE
short_name: TumE
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20126
counters:
  proteins: 1963
  matches: 1963
  proteomes: 1095
  taxa: 2207
  structures: 0
  alphafold_models: 1558
  domain_architectures: 4
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR045397
description: This entry represents a family of proteins found in archaea and bacteria. These proteins
  have been recently described as the toxin component TumE from the novel toxin-antitoxin system TumA,
  which constitutes a translation-targeting toxic effector [[cite:PUB00154744]]. These proteins are predicted
  to adopt a conserved alpha+beta fold, where two alpha-helices pack against an antiparallel beta-sheet
  with seven strands [[cite:PUB00154744]].