id: Pfam:PF20238
pfam_id: PF20238
name: Copper acquisition factor BIM1-like
short_name: BIM1-like_dom
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20238
counters:
  proteins: 4158
  matches: 4180
  proteomes: 1330
  taxa: 2901
  structures: 3
  alphafold_models: 3468
  domain_architectures: 50
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR046530
description: This domain is found in fungal proteins, including copper acquisition factor BIM1 from Cryptococcus
  neoformans, a cell-surface bound protein that functions in the copper-accumulation pathway shared by
  the CUF1-dependent copper transporter CTR1 [[cite:PUB00101283],[cite:PUB00101282]]. BIM1 facilitates
  copper acquisition in the brain of mammalian hosts and acts as a copper-dependent virulence trait in
  fungal meningitis [[cite:PUB00101283]]. This domain has a lytic polysaccharide monooxygenase-like (LPMO,
  [pfam:PF03067]) fold, which are evolutionarily related but have diverged to a different biological function.