id: Pfam:PF20410
pfam_id: PF20410
name: X-Tfes, XVIPCD
short_name: X-Tfes_XVIPCD
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20410
counters:
  proteins: 1260
  matches: 1263
  proteomes: 153
  taxa: 231
  structures: 2
  alphafold_models: 571
  domain_architectures: 40
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR046519
description: This conserved domain is found in Xanthomonas VirD4 interacting proteins (XVIPs) and other
  type IV secretion system (T4SS) specialised in translocating effector proteins (toxic effector proteins,
  X-Tfes) into competing gram-negative species, leading to target cell death. This domain interacts with
  the central all-alpha domain of VirD4. Its structure shows two well ordered N-terminal antiparallel
  alpha-helices that pack against a carboxyl-terminal three-stranded antiparallel beta sheet [[cite:PUB00151936],[cite:PUB00145392],[cite:PUB00151937]].