id: Pfam:PF21647
pfam_id: PF21647
name: CORD, C-terminal domain
short_name: CORD_C
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF21647
counters:
  proteins: 3244
  matches: 3782
  proteomes: 378
  taxa: 1045
  structures: 0
  alphafold_models: 2632
  domain_architectures: 83
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR049172
description: This domain is found at the C-terminal in Protein CORTICAL MICROTUBULE DISORDERING (CORD)
  proteins found in plants. This domain may consist of 5-6 alpha-helices. CORD proteins are microtubule-associated
  proteins that are required, redundantly with CORD2, for the formation of the pitted secondary cell wall
  of metaxylem vessels [[cite:PUB00163241]]. CORD1 from Arabidopsis thaliana controls the disorganisation
  of the parallel cortical microtubule network by modulating microtubule attachment to the plasma membrane
  in metaxylem vessel cells; this mechanism probably relies on disruption of interactions between ARAC10/ROP11
  and cortical microtubules [[cite:PUB00163241]5].