id: Pfam:PF21771
pfam_id: PF21771
name: CFAP58 central coiled coil
short_name: CFAP58_CC
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF21771
counters:
  proteins: 1966
  matches: 1999
  proteomes: 1289
  taxa: 4183
  structures: 5
  alphafold_models: 1726
  domain_architectures: 41
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR049270
description: This domain is found in Cilia- and flagella-associated protein 58 (CFAP58) and related eukaryotic
  proteins. The human CFAP58 protein has an essential role in the assembly and organisation of the sperm
  flagellar axoneme [[cite:PUB00151877]]. This domain forms a parallel coiled coil that in the C. reinhardtii
  axonemal structure lays on the doublet microtubule surface and interacts with the N terminus of the
  MIA coiled coil [[cite:PUB00152767]].