id: Pfam:PF21773
pfam_id: PF21773
name: ODAD1 central coiled coil region
short_name: ODAD1_CC
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF21773
counters:
  proteins: 3489
  matches: 3740
  proteomes: 1307
  taxa: 4258
  structures: 13
  alphafold_models: 3002
  domain_architectures: 65
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR049258
description: 'This domain, previously know as DUF6872, is found in Outer dynein arm-docking complex subunit
  1 (ODAD1, CCDC114) from humans and similar eukaryotic proteins. In mammals, CCDC114 forms a hetero-coiled
  coil with ODAD1/CCDC151 within the A07/A08 interprotofilament cleft, analogous to the DC1/2 coiled coil
  of the trimeric ODA-DC observed in C. reinhardtii axoneme [[cite:PUB00152762],[cite:PUB00100771]]. DC2
  is a homolog of the human ODAD1/CCDC151 and in C.reinhardtii it is a part of the ODA-DC that consists
  of three proteins: DC1, DC2, and DC3. The N-terminal halves of DC1 and DC2 form a microtubule-bound
  heteromeric coiled-coil [[cite:PUB00152762],[cite:PUB00152763]].'