id: Pfam:PF22751
pfam_id: PF22751
name: Active DUF488-N3 subclade
short_name: DUF488-N3a
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF22751
counters:
  proteins: 866
  matches: 866
  proteomes: 823
  taxa: 1522
  structures: 0
  alphafold_models: 552
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR054495
description: This entry represents a subclade of DUF488 domains with degenerate C-terminal core strand.
  Sometimes it is observed adjacent to the DUF488-s subclade, suggesting it preserves a catalytic activity
  comparable to other active DUF488 subclades [[cite:PUB00153826]].