id: Pfam:PF23147
pfam_id: PF23147
name: NAD-dependent glutamate dehydrogenase, N-terminal domain
short_name: GDH2_N
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23147
counters:
  proteins: 1740
  matches: 1741
  proteomes: 1561
  taxa: 3288
  structures: 0
  alphafold_models: 1450
  domain_architectures: 33
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR055480
description: This domain is found towards the N terminus of yeast NAD-specific glutamate dehydrogenase
  (GDH2, also known as DHE2) and similar fungal proteins. GDH2 is involved in the degradation of glutamate
  to ammonia and alpha-ketoglutarate. This domain is predicted to adopt a globular structure composed
  of four alpha-helices.