id: Pfam:PF24233
pfam_id: PF24233
name: Family of unknown function (DUF7446)
short_name: DUF7446
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF24233
counters:
  proteins: 149
  matches: 149
  proteomes: 144
  taxa: 384
  structures: 0
  alphafold_models: 46
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR055869
description: This entry represents a highly conserved domain found in various bacteriophages, particularly
  those infecting Salmonella and related bacteria. The domain is also present in some bacterial species,
  suggesting possible horizontal gene transfer. The function is unknown, but the high degree of conservation
  implies an important role in phage biology. A conserved motif DVT is present centrally in many family
  members. The aspartate and threonine form side chain hydrogen bonds that help stabilise the dimeric
  interaction. Structure prediction suggests these proteins form a confident homodimer (iPTM=0.83).