id: Pfam:PF24481
pfam_id: PF24481
name: CT398-like coiled coil hairpin domain
short_name: CT398_CC
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF24481
counters:
  proteins: 4456
  matches: 4456
  proteomes: 4444
  taxa: 6159
  structures: 3
  alphafold_models: 2705
  domain_architectures: 9
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR056003
description: This entry, previously known as DUF7581, represents a coiled coil hairpin domain found N-terminal
  in CT398 from C. trachomatis, MSMEG_4306 M. smegmatis and related bacterial sequences predominantly
  from actinobacteria. Both CT398 and MSMEG_4306 proteins have been structurally characterised [[cite:PUB00155616],[cite:PUB00156044]].
  CT398 protein is involved in several aspects of chlamydial biology and pathogenesis, and is capable
  of interacting with multiple binding partners. The coiled coil hairpin domain of CT398 engages in interaction
  with RpoN as well as both T3SS ATPase-regulators FliH and CdsL [[cite:PUB00156044]].