id: Pfam:PF24960
pfam_id: PF24960
name: Outer surface lipoprotein BB0158
short_name: BB0158
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF24960
counters:
  proteins: 145
  matches: 145
  proteomes: 31
  taxa: 53
  structures: 1
  alphafold_models: 86
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR056668
description: This domain, previously known as DUF7766, is found in Outer surface lipoprotein BB0158 from
  Borrelia burgdorferi and related proteins mainly from Spirochaetales. It folds into a double beta-barrel
  structure capped with alpha-helices PDB:8q4k. This domain forms a swapped dimer in which the N-terminal
  beta-strand from one monomer is replaced the N-terminal beta-strand from the other monomer [[cite:PUB00160310]].
  BB0158 is part of a family of paralogous proteins found in B. burgdorferi, known as paralogous gene
  family 44 (PFam44) [[cite:PUB00019466]]. This protein potentially plays a role in the pathogenesis of
  Lyme disease.