id: Pfam:PF25253
pfam_id: PF25253
name: DUF7855 N-terminal dimerisation domain
short_name: DUF7855
seed_status: KNOWN_HISTORICAL_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF25253
counters:
  proteins: 176
  matches: 176
  proteomes: 176
  taxa: 264
  structures: 0
  alphafold_models: 166
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR057177
description: This entry represents the N-terminal domain found in DUF7855 family proteins found in halobacteria.
  This domain is predicted to mediate dimerisation as well as DNA-binding. This domain belongs to the
  dimeric alpha/beta barrel superfamily. There is a notable pocket in each subunit beneath the DNA-binding
  interface that might might to a small molecule to regulate DNA-binding. The protein A0A371M7Z4 appears
  to bind to the DNA sequence GAGGTTACCTGGGCCAGGTAACCTC (pTM-0.9 iPTM=0.89).