id: Pfam:PF25559
pfam_id: PF25559
name: Domain of unknown function (DUF7931)
short_name: DUF7931
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF25559
counters:
  proteins: 941
  matches: 941
  proteomes: 938
  taxa: 1387
  structures: 0
  alphafold_models: 593
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR057691
description: This entry represents a domain of unknown function mostly found in bacteria. According to
  structure predictions it might adopt a phospholipase D/nuclease fold. Whilst the typical phospholipase
  D motif HxK(x)4D(x)6GSxN is not strictly conserved the overall fold suggests a potential distant evolutionary
  relationship to the PLD superfamily. The PLD nucleases can have endonuclease or exonuclease activity.
  These enzymes use the imidazole group of histidine as a nucleophile in their catalytic mechanism [[cite:PUB00152066],[cite:PUB00160607],[cite:PUB00024729]].