id: Pfam:PF25820
pfam_id: PF25820
name: Domain of unknown function (DUF7949)
short_name: DUF7949
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF25820
counters:
  proteins: 347
  matches: 358
  proteomes: 12
  taxa: 62
  structures: 0
  alphafold_models: 162
  domain_architectures: 53
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR057709
description: This entry describes a domain of unknown function in putative EGF-like domain-containing
  proteins found in eukaryotes, mainly ameobas. According to structure predictions it adopts an EGF-like
  fold which contain six conserved cysteine residues. The EGF-like fold has two-stranded beta-sheets followed
  by a loop to a short C-termini. It usually occurs in tandem repeats [[cite:PUB00001555]]. The domain
  described by this entry has the 6 conserved cysteine residues. It also acquires a similar structure
  to the EGF-like fold and it is 40 amino acids long.