id: Pfam:PF26397
pfam_id: PF26397
name: Domain of unknown function (DUF8097)
short_name: DUF8097
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26397
counters:
  proteins: 53
  matches: 53
  proteomes: 45
  taxa: 99
  structures: 0
  alphafold_models: 49
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR058410
description: This entry represents a family of small transmembrane proteins found exclusively in extremely
  halophilic archaea (Halobacteria). Members of this family typically contain two transmembrane helices
  with a conserved cytoplasmic region. Most proteins in this family are approximately 115-130 amino acids
  in length. The family is widely distributed across different genera within Halobacteriales, including
  Halococcus, Haloferax, Natrialba, Natronobacterium, and Haladaptatus. The specific function of these
  proteins remains unknown, but their conservation suggests they may play an important role in the adaptation
  to high-salt environments.