id: Pfam:PF26440
pfam_id: PF26440
name: Domain of unknown function (DUF8108) central domain
short_name: DUF8108_M
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26440
counters:
  proteins: 65
  matches: 65
  proteomes: 62
  taxa: 123
  structures: 0
  alphafold_models: 63
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR058963
description: This entry represents a the central transmembrane domain from family of uncharacterised proteins
  from halophilic archaea. The family is predominantly found in the class Halobacteria, which includes
  members from the families Natrialbaceae and Haloferacaceae. Proteins in this family are typically between
  150 and 350 amino acids in length. They are predicted to be membrane-associated, as suggested by the
  presence of two transmembrane helices represented by this domain.