id: Pfam:PF26473
pfam_id: PF26473
name: Domain of unknown function (DUF8148) N-terminal domain
short_name: DUF8148
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26473
counters:
  proteins: 35
  matches: 35
  proteomes: 26
  taxa: 62
  structures: 0
  alphafold_models: 24
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR058461
description: This entry represents the N-terminal winged helix domain from a family of uncharacterised
  proteins found predominantly in archaea, specifically within the Halobacteria class. The proteins in
  this family are typically found in species such as Halovenus, Halobellus, and Natrarchaeobaculum, among
  others. Additionally, some members are associated with viruses like the Pleolipoviridae family. The
  proteins containing this domain are predicted to be involved in replication processes, although their
  exact function remains unknown. The domain is found in proteins that are generally around 600-700 amino
  acids in length. These proteins are primarily associated with replication functions, as indicated by
  their presence in replication proteins across various archaeal species and viruses. The domain is sometimes
  found in association with other domains involved in replication, but specific domain associations are
  not consistently observed across all members of this family.