id: Pfam:PF26551
pfam_id: PF26551
name: Domain of unknown function (DUF8180)
short_name: DUF8180
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26551
counters:
  proteins: 280
  matches: 280
  proteomes: 256
  taxa: 541
  structures: 0
  alphafold_models: 203
  domain_architectures: 3
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR058493
description: This entry represents a domain from a family of uncharacterised proteins predominantly found
  in the class Clostridia. The proteins containing this domain are typically between 60 and 130 amino
  acids in length. The domain is highly conserved across various species within the Bacillota and Thermodesulfobacteriota
  phyla. Structure prediction suggests this protein is composed of two alpha helices and forms a head
  to tail dimer conformation. The sequences contain a set of histidines in helix one that according to
  AlphaFold 3 confidently binds to a zinc ion.