id: Pfam:PF26607
pfam_id: PF26607
name: PLL-like beta propeller
short_name: Beta-prop_PLL
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26607
counters:
  proteins: 3295
  matches: 3660
  proteomes: 1819
  taxa: 3095
  structures: 31
  alphafold_models: 1884
  domain_architectures: 208
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR058502
description: This domain, previously known as DUF8189, is found in the L-fucose-binding lectins PHL and
  PLLs(1-5) from various Photorhabdus species and their homologues. This domain forms a seven-bladed beta-propeller
  [[cite:PUB00100843],[cite:PUB00109482],[cite:PUB00161611]]. Each blade makes a W-motif composed of four
  antiparallel beta-strands (beta1-beta4) connected by beta-turns and loops. The C and N terminus are
  located on the same side of the torus and create a cap of the inner cavity of the torus. With exception
  of PLL3, which is a monomer, all other domains assemble into oligomeric structures, either homo-dimeric
  or homo-tetrameric, connected with an inter-subunit disulfide bridge [[cite:PUB00100843],[cite:PUB00109482],[cite:PUB00161611]].
  Besides L-fucose or fucosylated saccharides, some of these domains bind to unusual O-methylated disaccharide
  3,6-O-Me2-d-Glc-beta1-4(2,3-O-Me2)-l-Rha-alpha (MGMR) [[cite:PUB00161611]].