id: Pfam:PF27003
pfam_id: PF27003
name: Domain of unknown function (DUF8324)
short_name: DUF8324
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF27003
counters:
  proteins: 94
  matches: 126
  proteomes: 24
  taxa: 94
  structures: 0
  alphafold_models: 90
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR059368
description: This entry represents a domain of unknown function in uncharacterised proteins mostly from
  plants. This domain contains a Spectring fold with a conserved three-helix bundle structure that is
  typically arranged in tandem repeats. These repeats confer mechanical flexibility and structural resilience,
  allowing the proteins to maintain cell shape and organisation. Spectrin-repeat proteins form elongated
  scaffolds beneath the plasma membrane and contribute to cytoskeletal integrity and membrane stability.