id: Pfam:PF27032
pfam_id: PF27032
name: Domain of unknown function (DUF8340) N-terminal domain
short_name: DUF8340_N
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF27032
counters:
  proteins: 31
  matches: 31
  proteomes: 18
  taxa: 52
  structures: 0
  alphafold_models: 28
  domain_architectures: 5
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
description: This entry represents a domain of unknown function at the N-terminal in uncharacterised fungal
  proteins. This domain contains a RNases-like fold. The core architecture typically features a central
  five-stranded beta-sheet flanked by several alpha-helices. Most RNases H also possess an active site
  with a conserved DEDD motif (aspartate and glutamate residues), essential for coordinating catalytically
  required metal ions, usually Mg [[cite:PUB00016297]].