id: Pfam:PF27674
pfam_id: PF27674
name: Domain of unknown function (DUF8361)
short_name: DUF8361
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF27674
counters:
  proteins: 169
  matches: 187
  proteomes: 59
  taxa: 249
  structures: 0
  alphafold_models: 129
  domain_architectures: 11
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR059405
description: This domain is found in uncharacterised proteins from bacteria and eukaryotes. It is predicted
  to fold into a globular structure composed of a mixed beta-sheet and alpha-helices packed on both sides
  of it. It contains several conserved cysteine residues which are predicted to form disulfide bonds.
  In addition, there highly conserved aspartate, glutamate and histidine residues suggesting that some
  members may have enzymatic activity.