id: Pfam:PF28464
pfam_id: PF28464
name: Domain of unknown function (DUF8405)
short_name: DUF8405
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28464
counters:
  proteins: 202
  matches: 202
  proteomes: 158
  taxa: 303
  structures: 0
  alphafold_models: 126
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR059449
description: This domain is found in uncharacterised proteins from bacteria and eukaryotes. It is predicted
  to fold into an alpha/beta structure composed of four-stranded antiparallel beta-sheet with strand order
  2341 and alpha helices packed on one face of the sheet. This domain contains two pair of highly conserved
  cysteine residues that are predicted to form disulfide bonds. It is frequently found N-terminal to TIM-barrel
  domain.