id: Pfam:PF28527
pfam_id: PF28527
name: Domain of unknown function (DUF8425)
short_name: DUF8425
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28527
counters:
  proteins: 304
  matches: 304
  proteomes: 295
  taxa: 824
  structures: 0
  alphafold_models: 211
  domain_architectures: 28
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR059469
description: This domain is found in uncharacterised bacterial proteins. It is predicted to fold into
  an alpha-helical structure with similarity to 8-oxoguanine DNA glycosylase-like domains such as [pfam:PF22175]
  and [pfam:PF21790]. The structural similarity extends to the active site architecture with some of the
  active site residues conserved.