id: Pfam:PF28543
pfam_id: PF28543
name: Domain of unknown function (DUF8435)
short_name: DUF8435
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28543
counters:
  proteins: 287
  matches: 287
  proteomes: 106
  taxa: 239
  structures: 0
  alphafold_models: 278
  domain_architectures: 12
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR059479
description: This domain is found in a group of uncharacterised proteins from worms. This domain has highly
  conserved motifs YRF and HLRxRK and is predicted to show high structural similarity with UBA domains,
  which are often involved in ubiquitin binding. It is often found associated with [pfam:PF00650].