id: Pfam:PF28801
pfam_id: PF28801
name: Domain of unknown function (DUF8464)
short_name: DUF8464
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28801
counters:
  proteins: 1781
  matches: 1783
  proteomes: 828
  taxa: 1200
  structures: 0
  alphafold_models: 1199
  domain_architectures: 11
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061534
description: This entry represents the second domain found in bacterial DNA primases, positioned between
  the N-terminal zinc ribbon domain ([pfam:PF01807]) and the C-terminal Toprim domain ([pfam:PF13155]).
  This domain is approximately 65-70 amino acids in length and is found predominantly in DNA primases
  from Bacteroidota species, particularly members of the Bacteroidales order. DNA primase (DnaG) synthesises
  RNA primers that are utilised by DNA polymerase during bacterial chromosomal DNA replication. The specific
  function of this middle domain remains to be determined, but its conservation suggests it plays an important
  structural or functional role in primase activity within these bacteria.