id: Pfam:PF28811
pfam_id: PF28811
name: Domain of unknown function (DUF8466)
short_name: DUF8466
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28811
counters:
  proteins: 283
  matches: 283
  proteomes: 137
  taxa: 237
  structures: 0
  alphafold_models: 200
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061536
description: This entry represents a small domain of unknown function. It includes Porphyromonas gingivalis
  protein PGN_1290 [swissprot:B2RGS5] which was found to be down-regulated in a GppX mutant [[cite:PUB00163732]].
  This domain is composed of a four stranded beta sheet (strand order 1-4-3-2) with two alpha helices
  packed on one side. AlphaFold3 suggests these proteins form confident homodimers ([swissprot:R9HNH3]
  ipTM=0.9 pTM=0.92).