id: Pfam:PF28961
pfam_id: PF28961
name: Domain of unknown function (DUF8486)
short_name: DUF8486
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF28961
counters:
  proteins: 1341
  matches: 1341
  proteomes: 1029
  taxa: 1399
  structures: 0
  alphafold_models: 896
  domain_architectures: 7
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061556
description: This entry represents an N-terminal putative sensor domain found in histidine kinase proteins.
  This domain precedes the histidine kinase A (HisKA) phosphoacceptor domain ([pfam:PF00512]) and the
  histidine kinase ATPase C-terminal domain ([pfam:PF02518]). The domain is approximately 145-155 residues
  in length. This family is found predominantly in Bacteroidota, particularly in the orders Flavobacteriales,
  Cytophagales and Sphingobacteriales. The function of this sensor domain remains to be determined.