id: Pfam:PF29289
pfam_id: PF29289
name: Domain of unknown function (DUF8527)
short_name: DUF8527
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF29289
counters:
  proteins: 242
  matches: 242
  proteomes: 242
  taxa: 374
  structures: 0
  alphafold_models: 235
  domain_architectures: 1
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061597
description: This entry represents a small integral membrane domain of approximately 50-70 amino acids
  with two predicted transmembrane helices. The family is found exclusively in halophilic archaea, restricted
  to the order Halobacteriales, particularly the families Haloferacaceae, Natrialbaceae and Haloarculaceae.
  Some members are found in proteins containing PEP-CTERM protein-sorting domains. The function of this
  domain remains to be determined.