id: Pfam:PF30400
pfam_id: PF30400
name: Domain of unknown function (DUF8616)
short_name: DUF8616
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF30400
counters:
  proteins: 819
  matches: 968
  proteomes: 632
  taxa: 1086
  structures: 0
  alphafold_models: 215
  domain_architectures: 185
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061677
description: This entry represents a C-terminal domain found in RHS (rearrangement hotspot) family proteins
  and related polymorphic toxin proteins. It is often associated with ADP-ribosyltransferase toxin domains
  ([pfam:PF03496]) and RHS repeats ([pfam:PF03527]). In Escherichia coli K12, the domain is found in YibJ,
  which may be a pseudogene. The family is predominantly found in Actinomycetota, particularly Pseudonocardiaceae,
  and also in Proteobacteria. The function of this domain remains to be determined. Shows similarity to
  SteB family [pfam:PF29776] and [pfam:PF14252].