id: Pfam:PF30650
pfam_id: PF30650
name: Domain of unknown function (DUF8688)
short_name: DUF8688
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF30650
counters:
  proteins: 3160
  matches: 3160
  proteomes: 3148
  taxa: 3756
  structures: 0
  alphafold_models: 1742
  domain_architectures: 16
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061749
description: This entry represents an N-terminal helical domain of approximately 60 residues found in
  bacterial SAM-dependent methyltransferases. This domain is always located N-terminal to a methyltransferase
  domain ([pfam:PF09445], [pfam:PF13649]) and is frequently followed by a THUMP-like domain ([pfam:PF18096]).
  The family is found almost exclusively in Actinomycetota, particularly in Streptomyces species and related
  genera. The specific function of this N-terminal domain remains to be determined.