id: Pfam:PF30796
pfam_id: PF30796
name: Domain of unknown function (DUF8745)
short_name: DUF8745
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF30796
counters:
  proteins: 603
  matches: 604
  proteomes: 581
  taxa: 706
  structures: 0
  alphafold_models: 268
  domain_architectures: 6
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR061806
description: This entry represents an N-terminal domain of approximately 175 residues found in putative
  signal transduction proteins. Some members are annotated as histidine kinases or HSP90-like ATPases,
  and one example contains a HATPase_c domain ([pfam:PF02518]) suggesting these proteins function in two-component
  signalling systems. This domain may represent a sensor input domain. This family is found almost exclusively
  in Actinomycetota, particularly Streptomyces. The function of this domain remains to be determined.