1-Naphthylacetic acid

CHEBI:32918 chemically defined MAPPED CHEBI SYNONYM_MATCH

Ontology mapping

Primary identifier
CHEBI:32918
Ontology label
1-naphthaleneacetic acid
Notes
Imported from mim-queue (source_id=mediadive.ingredient:2436). Identity resolved 2026-06-14 to 1-naphthaleneacetic acid (NAA, CAS 86-87-3, CHEBI:32918) via Edison deep research; promoted to MAPPED 2026-06-15.

Synonyms (4)

SynonymTypeSourceOccurrences
1-Naphtylacetic Acid RAW_TEXT mim-queue
1-naphthylacetic acid EXACT_SYNONYM edison_deep_research
NAA ABBREVIATION edison_deep_research
naphthalen-1-ylacetic acid EXACT_SYNONYM chebi_synonym_review

Chemical properties

Cas rn
86-87-3
Data source
Edison/PaperQA3 deep research (janikova2020; henneberger; donnelly1990)
Retrieval date
2026-06-14T00:00:00+00:00
Molecular formula
C12H10O2
Smiles
O=C(O)Cc1cccc2ccccc12
Inchi
InChI=1S/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)
Molecular weight
186.21

Evidence (1)

DATABASE_MATCH via Edison/PaperQA3 deep research + local CHEBI verification

Source label "1-Naphtylacetic Acid" resolved to 1-naphthaleneacetic acid (NAA), CAS-RN 86-87-3; exact match to CHEBI:32918 verified in local chebi.db. Misspelling of "naphthyl".

Occurrence statistics

Total occurrences
0
Distinct media
0

Curation history

TimestampCuratorActionNew statusChanges
2026-04-30T18:43:03.698454+00:00 audit_import_ingredients[mim-queue] CREATED_AS_UNMAPPED UNMAPPED Imported from mim-queue (source_id=mediadive.ingredient:2436); no CAS-RN or CHEBI/NCIT match. Curator review needed.
2026-06-14T00:00:00+00:00 deep-research-ingredient-edison LLM RESEARCHED_IDENTITY UNMAPPED Edison/PaperQA3 deep research resolved the source spelling: "1-Naphtylacetic Acid" is 1-naphthaleneacetic acid (NAA), CAS-RN 86-87-3 (CHEBI:32918).
2026-06-15T00:00:00+00:00 promote_resolved_unmapped PROMOTED_TO_MAPPED MAPPED Promoted UNMAPPED_0316 → CHEBI:32918 "1-naphthaleneacetic acid" (EXACT_MATCH) after deep-research identity resolution; primary identifier updated, mapping_status UNMAPPED → MAPPED, SSSOM row added.
2026-08-10T00:00:00+00:00 regrade_synonym_matches REGRADED_EXACT_TO_SYNONYM mapping_quality EXACT_MATCH -> SYNONYM_MATCH (#317). The record's label does not equal the term's primary label '1-naphthaleneacetic acid'; it matches the ChEBI synonym 'NAA' on CHEBI:32918. The schema defines EXACT_MATCH as a direct match to the term and SYNONYM_MATCH as a match to a known synonym, so the recorded grade overstated. ontology_id is unchanged — the term is correct. The SSSOM predicate is unaffected (both grades emit skos:exactMatch).
2026-08-18T00:00:00+00:00 fix_naphthyl_spelling CORRECTED_PREFERRED_TERM_SPELLING Corrected the misspelling 'Naphtyl' -> 'Naphthyl' in preferred_term. This is not a regrounding: the record stays on CHEBI:32918 and denotes the same substance, and the record already carried '1-naphthylacetic acid' as a synonym, so the correct spelling was never in doubt. It matters now because kg-microbe overwrites an ontology term's canonical name from a symmetric SSSOM row, so this typo was published as the KG's name for CHEBI:32918 '1-naphthaleneacetic acid'. The raw misspelling is kept as a RAW_TEXT synonym so any source string still resolves — MAPPING_SEMANTICS warns that renaming a record removes the raw label downstream consumers match on, and keeping it as a synonym is what avoids that.

Knowledge gaps & discussions (1)

KNOWLEDGE_GAPOPEN Knowledge gap for 1-Naphtylacetic Acid: Despite their commercial popularity, numerous research gaps have limited the expansion of fundamental research and dogwood breeding programs.

Surfaced by the Europe PMC literature gap-signal scan (categories: explicit_gap, future_work, limitations_barriers, unclear_unknown). Curator review required: set attaches_to, refine the prompt, and weigh the cited evidence.

4 evidence item(s)
abstractNO_EVIDENCEPMID:41695534

Despite their commercial popularity, numerous research gaps have limited the expansion of fundamental research and dogwood breeding programs.

Gap-signal sentence (explicit_gap) from the cited abstract.

abstractNO_EVIDENCEPMID:40634860

Due to their heterogeneity and polygenic nature, the metabolic pathways and biological mechanisms underlying these conditions remain elusive.

Gap-signal sentence (unclear_unknown) from the cited abstract.

abstractNO_EVIDENCEPMID:40587842

However, the specific mechanisms by which gut bacteria and their metabolites exert therapeutic effects in melanoma remain poorly understood.

Gap-signal sentence (unclear_unknown) from the cited abstract.

abstractNO_EVIDENCEPMID:40110012

Despite extensive research, the exact causes and optimal treatment approaches for depression remain unclear.

Gap-signal sentence (unclear_unknown) from the cited abstract.