Ontology mapping
- Primary identifier
-
CHEBI:17905 - Ontology label
- coenzyme M
- kg-microbe node
CHEBI:17905
Nutritional roles
- Role
- COFACTOR_PROVIDER
- Confidence
- 0.6
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Assigned by in-session Claude reasoning (no external API)
- Curator note
- Provisional in-session LLM role assignment; review recommended.
Synonyms (17)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Cross-references: KEGG:com | RAW_TEXT | CultureMech | |
| 1-THIOETHANESULFONIC ACID | EXACT_SYNONYM | kg_microbe | |
| 2-Mercaptoethanesulfonic acid | EXACT_SYNONYM | kg_microbe | |
| 2-mercaptoethanesulphonic acid | EXACT_SYNONYM | kg_microbe | |
| 2-sulfanylethanesulfonic acid | EXACT_SYNONYM | kg_microbe | |
| 2-sulfanylethylsulfonate | EXACT_SYNONYM | kg_microbe | |
| CoM | EXACT_SYNONYM | kg_microbe | |
| Coenzym M | EXACT_SYNONYM | kg_microbe | |
| HS-CoM | EXACT_SYNONYM | kg_microbe | |
| beta-mercaptoethanesulfonic acid | EXACT_SYNONYM | kg_microbe | |
| coenzima M | EXACT_SYNONYM | kg_microbe | |
| reduced CoM | EXACT_SYNONYM | kg_microbe | |
| reduced coenzyme M | EXACT_SYNONYM | kg_microbe | |
| Coenzyme M | EXACT_SYNONYM | merged_from_duplicate_mim_record | |
| Role: Growth factor; Properties: Organic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| (sodium salt) | RAW_TEXT | CultureMech | |
| 2-Mercaptoethanesulfonic acid (Coenzyme M) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv |
Chemical properties
- Cas rn
- 3375-50-6
- Data source
- PubChem (via CHEBI:17905)
- Retrieval date
- 2026-04-09T00:32:50.689620+00:00
- Molecular formula
- C2H6O3S2
- Inchi
- InChI=1S/C2H6O3S2/c3-7(4,5)2-1-6/h6H,1-2H2,(H,3,4,5)
- Smiles
- O=S(=O)(O)CCS
Evidence (1)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Occurrence statistics
- Total occurrences
- 79
- Distinct media
- 79
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T21:52:12.067590+00:00 | fetch_cas_rn_from_cactus | ADDED_CAS_RN | MAPPED | Added CAS-RN:3375-50-6 from NCI CACTUS via name lookup (2-Mercaptoethanesulfonic acid) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 3375-50-6 from PubChem (via CHEBI:17905) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 12 synonyms from kg-microbe P4.4 enrichment: 1-THIOETHANESULFONIC ACID, 2-Mercaptoethanesulfonic acid, 2-mercaptoethanesulphonic acid, 2-sulfanylethanesulfonic acid, 2-sulfanylethylsulfonate, ... (7 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 11 synonyms from kg-microbe P4.4 enrichment: 1-THIOETHANESULFONIC ACID, 2-mercaptoethanesulphonic acid, 2-sulfanylethanesulfonic acid, 2-sulfanylethylsulfonate, CoM, ... (6 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 2 duplicate MIM record(s) into this one: Coenzyme_M.yaml, 2-mercaptoethanesulfonic_Acid.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:31.756568+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:27.555976+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C2H6O3S2; inchi=InChI=1S/C2H6O3S2/c3-7(4,5)2-1-6/h6H,1-2H2,(H,3,4,; smiles=O=S(=O)(O)CCS | |
| 2026-05-02T03:12:11.886725+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-06-09T04:56:30.247350+00:00 | claude_in_session_curation | ANNOTATED | Added media role: COFACTOR_PROVIDER (confidence: 0.60) | |
| 2026-06-09T05:23:46.707832+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label '2-Mercaptoethanesulfonate' -> 'coenzyme M': synced to canonical CHEBI label (preferred_term '2-Mercaptoethanesulfonate' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): COFACTOR_PROVIDER -> nutritional_roles.COFACTOR_PROVIDER | |
| 2026-08-27T03:16:39.518248+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 52/52 -> 79/79 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-08-30T04:48:06.233536+00:00 | claude_culturemech_alias_backfill | ADDED_SYNONYMS | Added 1 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: '2-Mercaptoethanesulfonic acid (Coenzyme M)' (x2 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv. |