alpha-Lactose

Ontology mapping

Primary identifier: CHEBI:189432
Ontology label: Alpha-lactose monohydrate

Nutritional roles

Role
CARBON_SOURCE
Confidence
0.7
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Inferred from CHEBI ancestry: subclass/has_role of CHEBI:16646 (carbohydrate)
  Curator note
  Provisional role inferred from CHEBI is_a/has_role closure; review recommended.
Role
ENERGY_SOURCE
Confidence
0.7
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Canonical energy substrate (catabolised for energy)
  Curator note
  Provisional ENERGY_SOURCE added alongside CARBON_SOURCE; review recommended.

Synonyms (6)

Synonym	Type	Source
beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose	EXACT_SYNONYM	chebi_synonym_review
1-beta-D-Galactopyranosyl-4-alpha-D-glucopyranose	RAW_TEXT	sssom_other_backfill
4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose	RAW_TEXT	sssom_other_backfill
Anhydrous lactose	RAW_TEXT	sssom_other_backfill
Milk sugar	RAW_TEXT	sssom_other_backfill
beta-D-Galp-(1->4)-alpha-D-Glcp	RAW_TEXT	sssom_other_backfill

Chemical properties

Cas rn: 5989-81-1
Data source: CultureBotHT compounds_to_cas.csv
Retrieval date: 2026-04-29T06:04:17.380972+00:00
Molecular formula: C12H22O11
Inchi: InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+/m1/s1
Smiles: OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

Evidence (2)

DATABASE_MATCH via CultureBotHT

Imported from CultureBotHT.

DATABASE_MATCH via MIM curation (#320)

identifier/ontology_id CHEBI:36219 ('alpha-lactose') -> CHEBI:189432 ('Alpha-lactose monohydrate'). The record's own cas_rn 5989-81-1 is registered by ChEBI against CHEBI:189432, which is the monohydrate of the term the record previously carried. Curation decision on #320: where the CAS names a more specific FORM than the label, the CAS governs — the recipe is taken to mean the substance actually weighed out. These surfaced as 'unrelated' in the ancestry triage only because ChEBI does not model salt-of / hydrate-of / racemate-of as subsumption, the same gap #342 recorded for hydrates.

Occurrence statistics

Total occurrences: 0
Distinct media: 0

Curation history

Timestamp	Curator	Action	New status	Changes
2026-04-29T06:04:17.380972+00:00	audit_integrate_culturebotht	CREATED_FROM_CULTUREBOTHT	MAPPED	Created from CultureBotHT compounds_to_cas.csv (CAS=5989-81-1); Imported from CultureBotHT.
2026-05-01T07:35:32.134375+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:27.957534+00:00	auto_classify_ingredient_type	AUTO_BACKFILL_CHEBI_CHEMISTRY		molecular_formula=C12H22O11; inchi=InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3); smiles=OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O
2026-05-02T03:12:12.411833+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-30T00:34:39.245219+00:00	infer_roles_from_chebi_ancestry	ANNOTATED		Added media role: CARBON_SOURCE (confidence: 0.70)
2026-06-04T05:38:59.200417+00:00	infer_energy_source	ANNOTATED		Added media role: ENERGY_SOURCE (confidence: 0.70)
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): CARBON_SOURCE -> nutritional_roles.CARBON_SOURCE; ENERGY_SOURCE -> nutritional_roles.ENERGY_SOURCE
2026-08-13T00:00:00+00:00	reground_cas_specific_form	REGROUNDED_TO_CAS_SPECIFIC_FORM		identifier/ontology_id CHEBI:36219 -> CHEBI:189432 'Alpha-lactose monohydrate' (#320); the record's CAS 5989-81-1 denotes the monohydrate. mapping_quality -> SYNONYM_MATCH.
2026-09-02T22:41:49.137449+00:00	claude_sssom_surface_form_backfill	ADDED_SYNONYMS		Recovered 5 surface form(s) that the published SSSOM `other` carried but no curated record did, so a rebuild would have dropped them from KGX: '1-beta-D-Galactopyranosyl-4-alpha-D-glucopyranose'; '4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose'; 'Anhydrous lactose'; 'Milk sugar'; 'beta-D-Galp-(1->4)-alpha-D-Glcp'. Tokens already present on the kg-microbe ontology node were left out as redundant (#520).