Ontology mapping
- Primary identifier
-
CHEBI:2682 - Ontology label
- amphotericin B
Physicochemical roles
- Role
- SELECTIVE_AGENT
- Confidence
- 0.8
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Inferred from curated media-role name pattern
- Curator note
- Provisional role from a curated name-pattern rule; review recommended.
Synonyms (8)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid | EXACT_SYNONYM | kg_microbe | |
| AMPH-B | EXACT_SYNONYM | kg_microbe | |
| Amphotericine B | EXACT_SYNONYM | kg_microbe | |
| Liposomal Amphotericin B | EXACT_SYNONYM | kg_microbe | |
| amfotericina B | EXACT_SYNONYM | kg_microbe | |
| amphotericinum B | EXACT_SYNONYM | kg_microbe | |
| Role: Antimicrobial agent | RAW_TEXT | CultureMech | |
| Amphotericin B (5 mg/ml DMSO) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv |
Chemical properties
- Cas rn
- 1397-89-3
- Data source
- PubChem API
- Retrieval date
- 2026-04-05T19:51:06.810414+00:00
- Molecular formula
- C47H73NO17
- Inchi
- InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
- Smiles
- [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(=O)O)O2
Evidence (1)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Occurrence statistics
- Total occurrences
- 4
- Distinct media
- 4
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:51:06.810459+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:1397-89-3 from PubChem API via name lookup (Amphotericin B) |
| 2026-04-05T21:52:24.942700+00:00 | fetch_cas_rn_from_cactus | ADDED_CAS_RN | MAPPED | Added CAS-RN:170451-78-2 from NCI CACTUS via name lookup (amphotericin B) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 6 synonyms from kg-microbe P4.4 enrichment: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid, AMPH-B, Amphotericine B, Liposomal Amphotericin B, amfotericina B, ... (1 more) |
| 2026-04-19T07:39:40.088622+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 1 duplicate MIM record(s) into this one: Amphotericin_B_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-04-19T07:39:40.088267+00:00 | audit_resolve_risky_cas_rn | RESOLVED_CAS_RN_CONFLICT | MAPPED | CAS-RN conflict across merged group (1397-89-3|170451-78-2) resolved via OAK canonical xref: 1397-89-3 (match) |
| 2026-05-01T07:35:32.174073+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:27.997127+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C47H73NO17; inchi=InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10; smiles=[H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N | |
| 2026-05-02T03:12:12.470756+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-06-02T07:05:13.386176+00:00 | infer_roles_from_name_lists | ANNOTATED | Added media role: SELECTIVE_AGENT (confidence: 0.80) | |
| 2026-06-09T05:23:46.723794+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Amphotericin B' -> 'amphotericin B': synced to canonical CHEBI label (preferred_term 'Amphotericin B' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): SELECTIVE_AGENT -> physicochemical_roles.SELECTIVE_AGENT | |
| 2026-08-27T03:16:39.518351+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 2/2 -> 4/4 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-08-30T04:48:06.233536+00:00 | claude_culturemech_alias_backfill | ADDED_SYNONYMS | Added 1 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'Amphotericin B (5 mg/ml DMSO)' (x1 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv. |