Ampicillin

CHEBI:28971 chemically defined MAPPED CHEBI EXACT_MATCH

Ontology mapping

Primary identifier
CHEBI:28971
Ontology label
ampicillin
kg-microbe node
CHEBI:28971

Physicochemical roles

Synonyms (18)

SynonymTypeSourceOccurrences
Role: Antimicrobial agent; Properties: Defined component, Organic compound, Simple component RAW_TEXT CultureMech
Role: Antimicrobial agent; Properties: Organic compound, Defined component, Simple component RAW_TEXT CultureMech
Role: Antimicrobial agent; Properties: Simple component, Defined component, Organic compound RAW_TEXT CultureMech
(2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID EXACT_SYNONYM kg_microbe
(2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid EXACT_SYNONYM kg_microbe
(2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid EXACT_SYNONYM kg_microbe
6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid EXACT_SYNONYM kg_microbe
6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid EXACT_SYNONYM kg_microbe
ABPC EXACT_SYNONYM kg_microbe
D-(-)-6-(alpha-aminophenylacetamido)penicillanic acid EXACT_SYNONYM kg_microbe
D-(-)-ampicillin EXACT_SYNONYM kg_microbe
aminobenzylpenicillin EXACT_SYNONYM kg_microbe
ampicilina EXACT_SYNONYM kg_microbe
ampicillin acid EXACT_SYNONYM kg_microbe
ampicilline EXACT_SYNONYM kg_microbe
ampicillinum EXACT_SYNONYM kg_microbe
Role: Antimicrobial agent; Properties: Organic compound, Solution, Defined component RAW_TEXT CultureMech
Ampicillin (50 mg/ml) RAW_TEXT culturemech:output/ingredient_occurrences.tsv

Chemical properties

Cas rn
69-53-4
Data source
PubChem API
Retrieval date
2026-04-05T19:51:07.335051+00:00
Molecular formula
C16H19N3O4S
Inchi
InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1
Smiles
[H][C@]12SC(C)(C)[C@H](C(=O)O)N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences
23
Distinct media
23

Curation history

TimestampCuratorActionNew statusChanges
2026-03-09T06:54:18.022301+00:00 import_from_culturemech IMPORTED MAPPED Initial import from CultureMech pipeline
2026-04-05T19:51:07.335099+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:69-53-4 from PubChem API via name lookup (Ampicillin)
2026-04-05T21:48:44.738811+00:00 fetch_cas_rn_from_culturebot_csv ADDED_CAS_RN MAPPED Added CAS-RN:69-52-3 from CultureBotHT compounds_to_cas.csv (matched: ampicillin)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 13 synonyms from kg-microbe P4.4 enrichment: (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (2S,6R)-6-{[(2R)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(D-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6beta-[(2R)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid, ... (8 more)
2026-04-19T07:39:40.088622+00:00 audit_mim_merge MERGED_FROM_DUPLICATES MAPPED Absorbed 1 duplicate MIM record(s) into this one: Ampicillin_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-04-19T07:39:40.088267+00:00 audit_resolve_risky_cas_rn RESOLVED_CAS_RN_CONFLICT MAPPED CAS-RN conflict across merged group (69-52-3|69-53-4) resolved via OAK canonical xref: 69-53-4 (match)
2026-05-01T07:35:32.180886+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:28.004615+00:00 auto_classify_ingredient_type AUTO_BACKFILL_CHEBI_CHEMISTRY molecular_formula=C16H19N3O4S; inchi=InChI=1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21); smiles=[H][C@]12SC(C)(C)[C@H](C(=O)O)N1C(=O)[C@H]2NC(=O)[
2026-05-02T03:12:12.479019+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-29T23:35:36.110147+00:00 extract_roles_from_synonyms ANNOTATED Added media role: SELECTIVE_AGENT (confidence: 1.00)
2026-06-09T05:23:46.723890+00:00 correct_stale_ontology_labels.py CORRECTED ontology_label 'Ampicillin' -> 'ampicillin': synced to canonical CHEBI label (preferred_term 'Ampicillin' unchanged).
2026-07-20T00:00:00+00:00 migrate_media_roles_to_facets ANNOTATED Migrated legacy media_roles to role facets (#128): SELECTIVE_AGENT -> physicochemical_roles.SELECTIVE_AGENT
2026-08-27T03:16:39.518354+00:00 refresh_occurrence_statistics CORRECTED occurrence_statistics 18/18 -> 23/23 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-08-30T04:48:06.233536+00:00 claude_culturemech_alias_backfill ADDED_SYNONYMS Added 1 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'Ampicillin (50 mg/ml)' (x2 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv.