Ontology mapping
- Primary identifier
-
CHEBI:41250 - Ontology label
- bis-tris
Physicochemical roles
- Role
- BUFFER
- Confidence
- 0.8
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Inferred from curated media-role name pattern
- Curator note
- Provisional role from a curated name-pattern rule; review recommended.
Synonyms (7)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Role: Buffer | RAW_TEXT | CultureMech | |
| 2,2-bis(hydroxymethyl)-2,2',2''-nitrilotriethanol | EXACT_SYNONYM | kg_microbe | |
| 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-1,3-propanediol | EXACT_SYNONYM | kg_microbe | |
| 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | EXACT_SYNONYM | kg_microbe | |
| 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol | EXACT_SYNONYM | kg_microbe | |
| BIS-2-HYDROXY-IMINO-TRIS-HYDROXYMETHYL-METHANE | EXACT_SYNONYM | kg_microbe | |
| bistris | EXACT_SYNONYM | kg_microbe |
Chemical properties
- Cas rn
- 6976-37-0
- Data source
- PubChem API
- Retrieval date
- 2026-04-05T19:51:14.069738+00:00
- Molecular formula
- C8H19NO5
- Inchi
- InChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
- Smiles
- OCCN(CCO)C(CO)(CO)CO
Evidence (1)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Occurrence statistics
- Total occurrences
- 4
- Distinct media
- 4
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:51:14.069789+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:6976-37-0 from PubChem API via name lookup (Bis-Tris) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 6 synonyms from kg-microbe P4.4 enrichment: 2,2-bis(hydroxymethyl)-2,2',2''-nitrilotriethanol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-1,3-propanediol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol, BIS-2-HYDROXY-IMINO-TRIS-HYDROXYMETHYL-METHANE, ... (1 more) |
| 2026-05-01T07:35:32.434898+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:28.246987+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C8H19NO5; inchi=InChI=1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-1; smiles=OCCN(CCO)C(CO)(CO)CO | |
| 2026-05-02T03:12:12.856324+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-06-03T02:06:01.736097+00:00 | infer_roles_from_name_lists | ANNOTATED | Added media role: BUFFER (confidence: 0.80) | |
| 2026-06-09T05:23:46.731205+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Bis-Tris' -> 'bis-tris': synced to canonical CHEBI label (preferred_term 'Bis-Tris' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): BUFFER -> physicochemical_roles.BUFFER | |
| 2026-08-27T03:16:39.518436+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 5/5 -> 4/4 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] |