Ontology mapping
- Primary identifier
-
CHEBI:15346 - Ontology label
- coenzyme A
- kg-microbe node
CHEBI:15346
Nutritional roles
- Role
- COFACTOR_PROVIDER
- Confidence
- 0.6
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Assigned by in-session Claude reasoning (no external API)
- Curator note
- Provisional in-session LLM role assignment; review recommended.
Synonyms (10)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Role: Growth factor; Properties: Organic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate} | EXACT_SYNONYM | kg_microbe | |
| 3'-phosphoadenosine-(5')diphospho(4')pantatheine | EXACT_SYNONYM | kg_microbe | |
| CoA-SH | EXACT_SYNONYM | kg_microbe | |
| CoASH | EXACT_SYNONYM | kg_microbe | |
| Coenzym A | EXACT_SYNONYM | kg_microbe | |
| HSCoA | EXACT_SYNONYM | kg_microbe | |
| Koenzym A | EXACT_SYNONYM | kg_microbe | |
| [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R)-3-hydroxy-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate | EXACT_SYNONYM | kg_microbe | |
| (sodium salt) | RAW_TEXT | CultureMech |
Chemical properties
- Cas rn
- 85-61-0
- Data source
- PubChem (via CHEBI:15346)
- Retrieval date
- 2026-04-09T00:32:50.689620+00:00
- Molecular formula
- C21H36N7O16P3S
- Inchi
- InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35)/t11-,14-,15-,16+,20-/m1/s1
- Smiles
- CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCS
Evidence (1)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Occurrence statistics
- Total occurrences
- 10
- Distinct media
- 10
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:51:31.042770+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:85-61-0 from PubChem API via name lookup (Coenzym A) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 85-61-0 from PubChem (via CHEBI:15346) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 8 synonyms from kg-microbe P4.4 enrichment: 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, CoA-SH, CoASH, Coenzym A, ... (3 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 8 synonyms from kg-microbe P4.4 enrichment: 3'-phosphoadenosine 5'-{3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl] dihydrogen diphosphate}, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, COENZYME A, CoA-SH, CoASH, ... (3 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 1 duplicate MIM record(s) into this one: Coenzym_A.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:32.868090+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:28.742339+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C21H36N7O16P3S; inchi=InChI=1S/C21H36N7O16P3S/c1-21(2,16(31)19(32)24-4-3; smiles=CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N | |
| 2026-05-02T03:12:13.481338+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-06-09T04:56:30.247833+00:00 | claude_in_session_curation | ANNOTATED | Added media role: COFACTOR_PROVIDER (confidence: 0.60) | |
| 2026-06-09T05:23:46.744407+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Coenzyme A' -> 'coenzyme A': synced to canonical CHEBI label (preferred_term 'Coenzyme A' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): COFACTOR_PROVIDER -> nutritional_roles.COFACTOR_PROVIDER | |
| 2026-08-27T03:16:39.518595+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 7/7 -> 10/10 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] |