Cycloheximid

CHEBI:27641 chemically defined MAPPED CHEBI EXACT_MATCH

Ontology mapping

Primary identifier
CHEBI:27641
Ontology label
cycloheximide

Physicochemical roles

Synonyms (10)

SynonymTypeSourceOccurrences
3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide EXACT_SYNONYM kg_microbe
4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione EXACT_SYNONYM kg_microbe
Cyclohexemid EXACT_SYNONYM kg_microbe
Cycloheximide EXACT_SYNONYM kg_microbe
Zykloheximid EXACT_SYNONYM kg_microbe
cicloheximida EXACT_SYNONYM kg_microbe
cicloheximide EXACT_SYNONYM kg_microbe
cicloheximidum EXACT_SYNONYM kg_microbe
naramycin EXACT_SYNONYM kg_microbe
naramycin A EXACT_SYNONYM kg_microbe

Chemical properties

Cas rn
66-81-9
Data source
PubChem API
Retrieval date
2026-04-05T19:51:38.827511+00:00
Molecular formula
C15H23NO4
Inchi
InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
Smiles
[H][C@@]1([C@H](O)CC2CC(=O)NC(=O)C2)C[C@@H](C)C[C@H](C)C1=O

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences
10
Distinct media
10

Curation history

TimestampCuratorActionNew statusChanges
2026-03-09T06:54:18.022301+00:00 import_from_culturemech IMPORTED MAPPED Initial import from CultureMech pipeline
2026-04-05T19:51:38.827543+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:66-81-9 from PubChem API via name lookup (Cycloheximid)
2026-04-07T10:19:13.158295+00:00 feba_ontology_enrichment_batch CREATED MAPPED Created ingredient file from FEBA ontology enrichment batch with ChEBI ID CHEBI:27641
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 10 synonyms from kg-microbe P4.4 enrichment: 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, Cyclohexemid, Cycloheximide, Zykloheximid, ... (5 more)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 10 synonyms from kg-microbe P4.4 enrichment: 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, Cyclohexemid, Cycloheximid, Zykloheximid, ... (5 more)
2026-04-19T07:39:23.955331+00:00 audit_mim_merge MERGED_FROM_DUPLICATES MAPPED Absorbed 1 duplicate MIM record(s) into this one: Cycloheximide.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-05-01T07:35:33.008355+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:28.915971+00:00 auto_classify_ingredient_type AUTO_BACKFILL_CHEBI_CHEMISTRY molecular_formula=C15H23NO4; inchi=InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5; smiles=[H][C@@]1([C@H](O)CC2CC(=O)NC(=O)C2)C[C@@H](C)C[C@
2026-05-02T03:12:13.664678+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-06-09T04:56:30.247850+00:00 claude_in_session_curation ANNOTATED Added media role: SELECTIVE_AGENT (confidence: 0.60)
2026-06-09T05:23:46.747856+00:00 correct_stale_ontology_labels.py CORRECTED ontology_label 'Cycloheximid' -> 'cycloheximide': synced to canonical CHEBI label (preferred_term 'Cycloheximid' unchanged).
2026-07-20T00:00:00+00:00 migrate_media_roles_to_facets ANNOTATED Migrated legacy media_roles to role facets (#128): SELECTIVE_AGENT -> physicochemical_roles.SELECTIVE_AGENT
2026-08-27T03:16:39.518667+00:00 refresh_occurrence_statistics CORRECTED occurrence_statistics 5/5 -> 10/10 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]