D-Glucose — MIM

Ontology mapping

Primary identifier: CHEBI:17634
Ontology label: D-glucose

Nutritional roles

Role
CARBON_SOURCE
Confidence
1.0
Evidence
- Reference text
  CultureMech database (710 occurrences as 'Carbon source')
  Reference type
  DATABASE_ENTRY
  Url
  https://github.com/CultureBotAI/CultureMech
  Excerpt
  Role: Carbon source; Properties: Defined component, Simple component, Organic compound
  Curator note
  Widespread use in media formulations (710 occurrences). High confidence based on 'Defined component' property.
Role
ENERGY_SOURCE
Confidence
0.7
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Canonical energy substrate (catabolised for energy)
  Curator note
  Provisional ENERGY_SOURCE added alongside CARBON_SOURCE; review recommended.

Synonyms (11)

Synonym	Type	Source
Cross-references: KEGG:glc_D	RAW_TEXT	CultureMech
Role: Carbon source; Properties: Defined component, Organic compound, Simple component	RAW_TEXT	CultureMech
Role: Carbon source; Properties: Defined component, Simple component, Organic compound	RAW_TEXT	CultureMech
Role: Carbon source; Properties: Organic compound, Defined component, Simple component	RAW_TEXT	CultureMech
Role: Carbon source; Properties: Organic compound, Simple component, Defined component	RAW_TEXT	CultureMech
D-(+)-glucose	EXACT_SYNONYM	kg_microbe
Traubenzucker	EXACT_SYNONYM	kg_microbe
D(+)-Glucose	EXACT_SYNONYM	merged_from_duplicate_mim_record
D-gluco-hexose	EXACT_SYNONYM	chebi_synonym_review
Dextrose	RAW_TEXT	MERGED_FROM_CHEBI:4167
aldehydo-D-glucose	RAW_TEXT	sssom_other_backfill

Chemical properties

Cas rn: 50-99-7
Data source: CultureBotHT/compounds_to_cas.csv
Retrieval date: 2026-04-09T00:32:50.689620+00:00
Molecular formula: C6H12O6

Evidence (2)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

LITERATURE SUPPORTvia PubMed search ('D-Glucose') PMID:33762358

Clinical localization of primary tumors and sites of metastasis by PET is based on the enhanced cellular uptake of 2-deoxy-2-[18F]-fluoro-D-glucose (FDG).

Auto-proposed; curator should rephrase or remove.

Occurrence statistics

Total occurrences: 1,250
Distinct media: 1,211

Curation history

Timestamp	Curator	Action	New status	Changes
2026-03-09T06:54:18.022301+00:00	import_from_culturemech	IMPORTED	MAPPED	Initial import from CultureMech pipeline
2026-04-05T19:51:43.118442+00:00	fetch_cas_rn_from_pubchem	ADDED_CAS_RN	MAPPED	Added CAS-RN:200-075-1 from PubChem API via name lookup (D-Glucose)
2026-04-05T23:44:03.918150+00:00	fetch_cas_rn_with_preprocessing	ADDED_CAS_RN	MAPPED	Added CAS-RN:200-075-1 from PubChem API (preprocessed) via name preprocessing (D(+)-Glucose)
2026-04-09T00:32:50.689620+00:00	enrich_mim_cas_rn_batch	CAS_RN_ADDED	MAPPED	Added CAS-RN 50-99-7 from CultureBotHT/compounds_to_cas.csv
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 2 synonyms from kg-microbe P4.4 enrichment: D-(+)-glucose, Traubenzucker
2026-04-19T07:39:23.955331+00:00	audit_mim_merge	MERGED_FROM_DUPLICATES	MAPPED	Absorbed 1 duplicate MIM record(s) into this one: D_-glucose.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-05-01T07:35:33.130460+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:29.056357+00:00	auto_classify_ingredient_type	AUTO_BACKFILL_CHEBI_CHEMISTRY		molecular_formula=C6H12O6
2026-05-01T08:09:47.813986+00:00	auto_classify_ingredient_type	APPLY_EVIDENCE_PROPOSAL		added pmid=33762358 from propose-evidence batch
2026-05-02T03:12:13.837048+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-29T23:35:36.110880+00:00	extract_roles_from_synonyms	ANNOTATED		Added media role: CARBON_SOURCE (confidence: 1.00)
2026-06-04T05:38:59.200655+00:00	infer_energy_source	ANNOTATED		Added media role: ENERGY_SOURCE (confidence: 0.70)
2026-06-09T05:23:46.751890+00:00	correct_stale_ontology_labels.py	CORRECTED		ontology_label 'D-Glucose' -> 'D-glucose': synced to canonical CHEBI label (preferred_term 'D-Glucose' unchanged).
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): CARBON_SOURCE -> nutritional_roles.CARBON_SOURCE; ENERGY_SOURCE -> nutritional_roles.ENERGY_SOURCE
2026-08-13T00:00:00+00:00	merge_glucose_family	MERGED_FROM		Absorbed 'Dextrose' (#320/#334), which sat on CHEBI:4167 ('D-glucopyranose'). Merged because dextrose is D-glucose; CHEBI:4167 'D-glucopyranose' is the cyclic pyranose form, a ring conformation the label does not name. Both records carry the same CAS 50-99-7 and the same formula C6H12O6. Four MIM records for glucose carried the identical CAS and formula while sitting on four different ChEBI terms, split only by where lexical matching landed. Occurrences 710/100 + 103/50 -> 813/150. Raw label kept as a RAW_TEXT synonym.
2026-08-27T03:16:39.518701+00:00	refresh_occurrence_statistics	CORRECTED		occurrence_statistics 150/813 -> 1211/1250 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-09-02T22:41:49.137449+00:00	claude_sssom_surface_form_backfill	ADDED_SYNONYMS		Recovered 1 surface form(s) that the published SSSOM `other` carried but no curated record did, so a rebuild would have dropped them from KGX: 'aldehydo-D-glucose'. Tokens already present on the kg-microbe ontology node were left out as redundant (#520).