DL-Malic acid

CHEBI:6650 chemically defined MAPPED CHEBI EXACT_MATCH

Ontology mapping

Primary identifier
CHEBI:6650
Ontology label
malic acid
kg-microbe node
CHEBI:6650

Nutritional roles

Synonyms (15)

SynonymTypeSourceOccurrences
Role: Carbon source; Properties: Organic compound, Defined component, Simple component RAW_TEXT CultureMech
2-Hydroxybutanedioic acid EXACT_SYNONYM kg_microbe
2-Hydroxyethane-1,2-dicarboxylic acid EXACT_SYNONYM kg_microbe
2-Hydroxysuccinic acid EXACT_SYNONYM kg_microbe
Aepfelsaeure EXACT_SYNONYM kg_microbe
D,L-Malic Acid EXACT_SYNONYM kg_microbe
E296 EXACT_SYNONYM kg_microbe
H2mal EXACT_SYNONYM kg_microbe
alpha-hydroxysuccinic acid EXACT_SYNONYM kg_microbe
apple acid EXACT_SYNONYM kg_microbe
hydroxybutanedioic acid EXACT_SYNONYM kg_microbe
hydroxysuccinic acid EXACT_SYNONYM kg_microbe
Malic acid EXACT_SYNONYM merged_from_duplicate_mim_record
DL-Malate EXACT_SYNONYM merged_from_duplicate_mim_record
Role: Carbon source; Properties: Organic compound, Simple component, Defined component RAW_TEXT CultureMech

Rejected enrichment labels (2)

Provenance-only candidates: these are not synonyms and do not resolve to this record.

Rejected labelDispositionSourceOccurrences
7,10-dihydroxy-2-(2-methoxypropan-2-yl)-8-(2-methylbut-3-en-2-yl)-6H-furo[3,2-c]xanthen-6-one REJECTED_LABEL kg_microbe
garciniaxanthone F REJECTED_LABEL kg_microbe

Chemical properties

Cas rn
6915-15-7
Data source
PubChem API
Retrieval date
2026-04-05T19:51:56.300919+00:00
Molecular formula
C4H6O5
Inchi
InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
Smiles
O=C(O)CC(O)C(=O)O

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences
42
Distinct media
42

Curation history

TimestampCuratorActionNew statusChanges
2026-03-09T06:54:18.022301+00:00 import_from_culturemech IMPORTED MAPPED Initial import from CultureMech pipeline
2026-04-05T19:51:55.818442+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:149-61-1 from PubChem API via name lookup (DL-Malate)
2026-04-05T19:51:56.300970+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:6915-15-7 from PubChem API via name lookup (DL-Malic acid)
2026-04-05T23:44:09.793163+00:00 fetch_cas_rn_with_preprocessing ADDED_CAS_RN MAPPED Added CAS-RN:6915-15-7 from PubChem API (ontology label) via name preprocessing (DL-malic acid)
2026-04-09T00:32:50.689620+00:00 enrich_mim_cas_rn_batch CAS_RN_ADDED MAPPED Added CAS-RN 6915-15-7 from PubChem (via CHEBI:6650)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 11 synonyms from kg-microbe P4.4 enrichment: 2-Hydroxybutanedioic acid, 2-Hydroxyethane-1,2-dicarboxylic acid, 2-Hydroxysuccinic acid, Aepfelsaeure, D,L-Malic Acid, ... (6 more)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 12 synonyms from kg-microbe P4.4 enrichment: 2-Hydroxybutanedioic acid, 2-Hydroxyethane-1,2-dicarboxylic acid, 2-Hydroxysuccinic acid, Aepfelsaeure, D,L-Malic Acid, ... (7 more)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM REMAPPED MAPPED Remapped CHEBI:65947 (garciniaxanthone F) → CHEBI:6650 (malic acid). Original CHEBI was an unrelated xanthone natural product.
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 2 synonyms from kg-microbe P4.4 enrichment: 7,10-dihydroxy-2-(2-methoxypropan-2-yl)-8-(2-methylbut-3-en-2-yl)-6H-furo[3,2-c]xanthen-6-one, garciniaxanthone F
2026-04-19T07:39:40.088622+00:00 audit_mim_merge MERGED_FROM_DUPLICATES MAPPED Absorbed 3 duplicate MIM record(s) into this one: Malic_Acid.yaml, Dl-malate.yaml, Dl-malic_Acid_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-04-19T07:39:40.088267+00:00 audit_resolve_risky_cas_rn RESOLVED_CAS_RN_CONFLICT MAPPED CAS-RN conflict across merged group (149-61-1|6915-15-7) resolved via OAK canonical xref: 6915-15-7 (match)
2026-05-01T07:35:33.360969+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:29.332917+00:00 auto_classify_ingredient_type AUTO_BACKFILL_CHEBI_CHEMISTRY molecular_formula=C4H6O5; inchi=InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,; smiles=O=C(O)CC(O)C(=O)O
2026-05-02T03:12:14.141815+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-29T23:35:36.111009+00:00 extract_roles_from_synonyms ANNOTATED Added media role: CARBON_SOURCE (confidence: 1.00)
2026-06-04T05:38:59.200724+00:00 infer_energy_source ANNOTATED Added media role: ENERGY_SOURCE (confidence: 0.70)
2026-06-09T05:23:46.758302+00:00 correct_stale_ontology_labels.py CORRECTED ontology_label 'DL-Malic acid' -> 'malic acid': synced to canonical CHEBI label (preferred_term 'DL-Malic acid' unchanged).
2026-07-20T00:00:00+00:00 migrate_media_roles_to_facets ANNOTATED Migrated legacy media_roles to role facets (#128): CARBON_SOURCE -> nutritional_roles.CARBON_SOURCE; ENERGY_SOURCE -> nutritional_roles.ENERGY_SOURCE
2026-08-27T03:16:39.518770+00:00 refresh_occurrence_statistics CORRECTED occurrence_statistics 18/18 -> 42/42 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-09-20T00:00:00Z retire_wrong_compound_synonyms LLM CORRECTED Marked 2 synonym(s) non-resolving: ['7,10-dihydroxy-2-(2-methoxypropan-2-yl)-8-(2-methylbut-3-en-2-yl)-6H-furo[3,2-c]xanthen-6-one', 'garciniaxanthone F']. ChEBI gives these names to CHEBI:65947, not to this record's CHEBI:6650 -- malic acid is not garciniaxanthone F. Kept as REJECTED_LABEL so a rebuild cannot restore them from kg-microbe's synonym list (#669).