Folinic acid

CHEBI:15640 chemically defined MAPPED CHEBI SYNONYM_MATCH

Ontology mapping

Primary identifier
CHEBI:15640
Ontology label
5-formyltetrahydrofolic acid

Nutritional roles

Synonyms (2)

SynonymTypeSourceOccurrences
(calcium salt) RAW_TEXT CultureMech
N-[4-({[2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid EXACT_SYNONYM chebi_synonym_review

Chemical properties

Cas rn
58-05-9
Data source
PubChem API
Retrieval date
2026-04-05T19:52:10.509002+00:00
Molecular formula
C20H23N7O7
Inchi
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1
Smiles
[H]C(=O)N1c2c(nc(N)nc2=O)NCC1CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences
2
Distinct media
2

Curation history

TimestampCuratorActionNew statusChanges
2026-03-09T06:54:18.022301+00:00 import_from_culturemech IMPORTED MAPPED Initial import from CultureMech pipeline
2026-04-05T19:52:10.509034+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:58-05-9 from PubChem API via name lookup (Folinic acid)
2026-04-19T01:05:11.441736+00:00 cbclaw_sssom_review_fix CORRECTED_ONTOLOGY_ID MAPPED Corrected ontology_id CHEBI:42521 -> CHEBI:15640 (old label: 'Folinic acid', new label: '5-formyltetrahydrofolic acid'). Reason: Previous CHEBI:42521 no longer resolves in CHEBI. Stripped 0 kg_microbe-sourced synonyms that were contaminated by the wrong CHEBI.
2026-05-01T07:35:33.670085+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:29.643919+00:00 auto_classify_ingredient_type AUTO_BACKFILL_CHEBI_CHEMISTRY molecular_formula=C20H23N7O7; inchi=InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27; smiles=[H]C(=O)N1c2c(nc(N)nc2=O)NCC1CNc1ccc(C(=O)N[C@@H](
2026-05-02T03:12:14.546732+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-30T00:34:39.425393+00:00 infer_roles_from_chebi_ancestry ANNOTATED Added media role: VITAMIN_SOURCE (confidence: 0.70)
2026-07-20T00:00:00+00:00 migrate_media_roles_to_facets ANNOTATED Migrated legacy media_roles to role facets (#128): VITAMIN_SOURCE -> nutritional_roles.VITAMIN_SOURCE
2026-08-10T00:00:00+00:00 regrade_synonym_matches REGRADED_EXACT_TO_SYNONYM mapping_quality EXACT_MATCH -> SYNONYM_MATCH (#317). The record's label does not equal the term's primary label '5-formyltetrahydrofolic acid'; it matches the ChEBI synonym 'Folinic acid' on CHEBI:15640. The schema defines EXACT_MATCH as a direct match to the term and SYNONYM_MATCH as a match to a known synonym, so the recorded grade overstated. ontology_id is unchanged — the term is correct. The SSSOM predicate is unaffected (both grades emit skos:exactMatch).
2026-08-27T03:16:39.518902+00:00 refresh_occurrence_statistics CORRECTED occurrence_statistics 1/1 -> 2/2 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]