Ontology mapping
- Primary identifier
-
CHEBI:17716 - Ontology label
- lactose
Nutritional roles
- Role
- CARBON_SOURCE
- Confidence
- 1.0
- Evidence
- Reference type
- DATABASE_ENTRY
- Reference text
- Imported from CultureMech pipeline
- Curator note
- Original role text: Carbon Source
- Role
- ENERGY_SOURCE
- Confidence
- 0.7
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Canonical energy substrate (catabolised for energy)
- Curator note
- Provisional ENERGY_SOURCE added alongside CARBON_SOURCE; review recommended.
Synonyms (28)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Cross-references: KEGG:lcts | RAW_TEXT | CultureMech | |
| Role: Carbon source; Properties: Defined component, Organic compound, Simple component | RAW_TEXT | CultureMech | |
| Role: Carbon source; Properties: Defined component, Simple component, Organic compound | RAW_TEXT | CultureMech | |
| Role: Carbon source; Properties: Organic compound, Simple component, Defined component | RAW_TEXT | CultureMech | |
| Role: Carbon source; Properties: Simple component, Organic compound, Defined component | RAW_TEXT | CultureMech | |
| (+)-lactose | EXACT_SYNONYM | kg_microbe | |
| 1-beta-D-Galactopyranosyl-4-D-glucopyranose | EXACT_SYNONYM | kg_microbe | |
| 4-(beta-D-galactosido)-D-glucose | EXACT_SYNONYM | kg_microbe | |
| 4-O-beta-D-galactopyranosyl-D-glucose | EXACT_SYNONYM | kg_microbe | |
| 4-O-beta-D-galactopyranosyl-beta-D-glucopyranose | EXACT_SYNONYM | kg_microbe | |
| D-lactose | EXACT_SYNONYM | kg_microbe | |
| D-lactose (lactose) | EXACT_SYNONYM | kg_microbe | |
| Galb1-4Glcb | EXACT_SYNONYM | kg_microbe | |
| Galbeta1-4Glc | EXACT_SYNONYM | kg_microbe | |
| Galbeta1-4Glcbeta | EXACT_SYNONYM | kg_microbe | |
| Lac | EXACT_SYNONYM | kg_microbe | |
| Laktobiose | EXACT_SYNONYM | kg_microbe | |
| Laktose | EXACT_SYNONYM | kg_microbe | |
| Milchzucker | EXACT_SYNONYM | kg_microbe | |
| beta lactose | EXACT_SYNONYM | kg_microbe | |
| beta-D-Gal-(1->4)-D-Glc | EXACT_SYNONYM | kg_microbe | |
| beta-D-Galp-(1->4)-D-Glcp | EXACT_SYNONYM | kg_microbe | |
| beta-D-Galp-(1->4)-beta-D-Glcp | EXACT_SYNONYM | kg_microbe | |
| beta-D-galactopyranosyl-(1->4)-D-glucopyranose | EXACT_SYNONYM | chebi_synonym_review | |
| (2)-D-lactose | RAW_TEXT | microbedecoder | |
| beta-D-Lactose | RAW_TEXT | sssom_other_backfill | |
| beta-D-galactopyranosyl-(1->4)-beta-D-glucose | RAW_TEXT | sssom_other_backfill | |
| beta-D-glucopyranose, 4-O-beta-D-galactopyranosyl- | RAW_TEXT | sssom_other_backfill |
Rejected enrichment labels (1)
Provenance-only candidates: these are not synonyms and do not resolve to this record.
| Rejected label | Disposition | Source | Occurrences |
|---|---|---|---|
| Lactose monohydrate | REJECTED_LABEL | sssom_other_backfill |
Chemical properties
- Cas rn
- 63-42-3
- Data source
- PubChem (via CHEBI:17716)
- Retrieval date
- 2026-04-09T00:32:50.689620+00:00
- Molecular formula
- C12H22O11
- Inchi
- InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11?,12+/m1/s1
- Smiles
- OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
Evidence (2)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
Investigation of factors that affect stability, growth, and induction of T7 expression strains in shaking vessels led to the recognition that sporadic, unintended induction of expression in complex media, previously reported by others, is almost certainly caused by small amounts of lactose.
Auto-proposed; curator should rephrase or remove.
Occurrence statistics
- Total occurrences
- 55
- Distinct media
- 55
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:52:47.460837+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:200-559-2 from PubChem API via name lookup (Lactose) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 63-42-3 from PubChem (via CHEBI:17716) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 18 synonyms from kg-microbe P4.4 enrichment: (+)-lactose, 1-beta-D-Galactopyranosyl-4-D-glucopyranose, 4-(beta-D-galactosido)-D-glucose, 4-O-beta-D-galactopyranosyl-D-glucose, 4-O-beta-D-galactopyranosyl-beta-D-glucopyranose, ... (13 more) |
| 2026-05-01T07:35:34.474012+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:30.494341+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=C12H22O11; inchi=InChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3); smiles=OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H | |
| 2026-05-01T08:09:47.931549+00:00 | auto_classify_ingredient_type | APPLY_EVIDENCE_PROPOSAL | added pmid=15915565 from propose-evidence batch | |
| 2026-05-02T03:12:15.691089+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-05-29T23:35:36.111703+00:00 | extract_roles_from_synonyms | ANNOTATED | Added media role: CARBON_SOURCE (confidence: 1.00) | |
| 2026-06-04T05:38:59.200963+00:00 | infer_energy_source | ANNOTATED | Added media role: ENERGY_SOURCE (confidence: 0.70) | |
| 2026-06-09T05:23:46.787743+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Lactose' -> 'lactose': synced to canonical CHEBI label (preferred_term 'Lactose' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): CARBON_SOURCE -> nutritional_roles.CARBON_SOURCE; ENERGY_SOURCE -> nutritional_roles.ENERGY_SOURCE | |
| 2026-08-06T05:15:48.923652+00:00 | issue_213_grounding LLM | MERGED_FROM_UNMAPPED_DUPLICATE | Absorbed UNMAPPED_0694 '(2)-D-lactose' as a RAW_TEXT synonym -- Parse artifact: the leading '(2)' is stray text, the substance is D-lactose (#213). No new SSSOM row; CHEBI:17716 is already mapped. Source: kgmicrobe.trait:2_d_lactose. | |
| 2026-08-27T03:16:39.519198+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 38/38 -> 55/55 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-09-02T22:41:49.137449+00:00 | claude_sssom_surface_form_backfill | ADDED_SYNONYMS | Recovered 4 surface form(s) that the published SSSOM `other` carried but no curated record did, so a rebuild would have dropped them from KGX: 'Lactose monohydrate'; 'beta-D-Lactose'; 'beta-D-galactopyranosyl-(1->4)-beta-D-glucose'; 'beta-D-glucopyranose, 4-O-beta-D-galactopyranosyl-'. Tokens already present on the kg-microbe ontology node were left out as redundant (#520). | |
| 2026-09-12T00:00:00+00:00 | reject_hidden_hydrate_synonym_collapses | REJECTED_HIDDEN_HYDRATE_SYNONYMS | MAPPED | Marked hidden hydrate synonym(s) as REJECTED_LABEL so this record no longer resolves sibling hydrate identities (#251): 'Lactose monohydrate'. |