Na2 alpha-ketoglutarate

kgmicrobe.compound:na2_alpha-ketoglutarate chemically defined MAPPED CHEBI NARROW_MATCH

Ontology mapping

Primary identifier
kgmicrobe.compound:na2_alpha-ketoglutarate
Ontology term
CHEBI:30915 — 2-oxoglutaric acid
Ontology label
2-oxoglutaric acid
kg-microbe node
kgmicrobe.compound:na2_alpha-ketoglutarate

Nutritional roles

Synonyms (2)

SynonymTypeSourceOccurrences
Na2 α-ketoglutarate EXACT_SYNONYM kg_microbe
Role: Growth factor RAW_TEXT CultureMech

Rejected enrichment labels (4)

Provenance-only candidates: these are not synonyms and do not resolve to this record.

Rejected labelDispositionSourceOccurrences
2-Oxoglutarate REJECTED_LABEL kg_microbe
2-oxopentanedioate REJECTED_LABEL kg_microbe
alpha-ketoglutarate REJECTED_LABEL kg_microbe
α-Ketoglutarate REJECTED_LABEL culturemech:output/ingredient_occurrences.tsv

Evidence (2)

DATABASE_MATCH via CultureMech

SUPERSEDED (#315): describes the bare ion identity, not the complete salt or ion pair. Original note follows. Imported from CultureMech pipeline, quality=DIRECT_MATCH

CURATOR_JUDGMENT via MIM curation (#315)

The label names a disodium salt, not the 2-oxoglutarate dianion in CHEBI:16810; CHEBI:30915 is the ChEBI acid parent. No exact local ChEBI term for 'Na2 alpha-ketoglutarate' was found, so MAPPING_SEMANTICS.md Section 3 uses a kgmicrobe.compound identity with the nearest ChEBI parent.

Occurrence statistics

Total occurrences
4
Distinct media
4

Curation history

TimestampCuratorActionNew statusChanges
2026-03-09T06:54:18.022301+00:00 import_from_culturemech IMPORTED MAPPED Initial import from CultureMech pipeline
2026-04-05T19:50:53.117580+00:00 fetch_cas_rn_from_pubchem ADDED_CAS_RN MAPPED Added CAS-RN:328-50-7 from PubChem API via name lookup (2-Oxoglutarate)
2026-04-09T00:32:50.689620+00:00 enrich_mim_cas_rn_batch CAS_RN_ADDED MAPPED Added CAS-RN 64-15-3 from PubChem (via CHEBI:16810)
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 4 synonyms from kg-microbe P4.4 enrichment: 2-Oxoglutarate, 2-oxopentanedioate, Na2 α-ketoglutarate, alpha-ketoglutarate
2026-04-18T00:00:00+00:00 cbclaw_kg_microbe_sweep LLM ADDED_SYNONYMS MAPPED Added 4 synonyms from kg-microbe P4.4 enrichment: 2-oxopentanedioate, Na2 alpha-ketoglutarate, Na2 α-ketoglutarate, alpha-ketoglutarate
2026-04-19T07:39:40.088622+00:00 audit_mim_merge MERGED_FROM_DUPLICATES MAPPED Absorbed 1 duplicate MIM record(s) into this one: 2-oxoglutarate.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-04-19T07:39:40.088267+00:00 audit_resolve_risky_cas_rn RESOLVED_CAS_RN_CONFLICT MAPPED CAS-RN conflict across merged group (328-50-7|64-15-3) resolved via OAK canonical xref: 64-15-3 (match)
2026-05-01T07:35:35.117809+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:31.183153+00:00 auto_classify_ingredient_type AUTO_BACKFILL_CHEBI_CHEMISTRY molecular_formula=C5H4O5; inchi=InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,; smiles=O=C([O-])CCC(=O)C(=O)[O-]
2026-05-02T03:12:16.916048+00:00 auto_classify_ingredient_type AUTO_CLASSIFY_INGREDIENT_TYPE set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-06-03T03:22:14.592020+00:00 infer_roles_from_name_lists ANNOTATED Added media role: CARBON_SOURCE (confidence: 0.80)
2026-06-04T05:38:59.201108+00:00 infer_energy_source ANNOTATED Added media role: ENERGY_SOURCE (confidence: 0.70)
2026-06-09T05:23:46.805587+00:00 correct_stale_ontology_labels.py CORRECTED ontology_label 'Na2 alpha-ketoglutarate' -> '2-oxoglutarate(2-)': synced to canonical CHEBI label (preferred_term 'Na2 alpha-ketoglutarate' unchanged).
2026-07-20T00:00:00+00:00 migrate_media_roles_to_facets ANNOTATED Migrated legacy media_roles to role facets (#128): CARBON_SOURCE -> nutritional_roles.CARBON_SOURCE; ENERGY_SOURCE -> nutritional_roles.ENERGY_SOURCE
2026-08-10T00:00:00+00:00 regrade_synonym_matches REGRADED_EXACT_TO_SYNONYM mapping_quality EXACT_MATCH -> SYNONYM_MATCH (#317). The record's label does not equal the term's primary label '2-oxoglutarate(2-)'; it matches the ChEBI synonym '2-oxoglutarate' on CHEBI:16810. The schema defines EXACT_MATCH as a direct match to the term and SYNONYM_MATCH as a match to a known synonym, so the recorded grade overstated. ontology_id is unchanged — the term is correct. The SSSOM predicate is unaffected (both grades emit skos:exactMatch).
2026-08-27T03:16:39.519442+00:00 refresh_occurrence_statistics CORRECTED occurrence_statistics 4/4 -> 7/7 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-08-31T23:56:54.854807+00:00 claude_culturemech_alias_backfill ADDED_SYNONYMS Added 1 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'α-Ketoglutarate' (x3 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv.
2026-09-11T06:31:23.789310+00:00 fix_salt_ion_identity_overclaims REGROUNDED_ION_OVERCLAIM MAPPED identifier CHEBI:16810 -> kgmicrobe.compound:na2_alpha-ketoglutarate; mapping_quality -> NARROW_MATCH to CHEBI:30915 ('2-oxoglutaric acid'). Cleared chemical_properties because they described the 2-oxoglutarate dianion only, marked 4 bare-ion synonym(s) as REJECTED_LABEL, and kept the complete salt or ion-pair identity distinct (#315).
2026-09-11T09:57:00+00:00 fix_salt_ion_identity_overclaims CORRECTED occurrence_statistics 7/7 -> 4/4 (media_count/total_occurrences) to match label-aware CultureMech membership routing after the salt/anion split (#315).