Ontology mapping
- Primary identifier
-
CHEBI:34683 - Ontology label
- disodium hydrogenphosphate
- kg-microbe node
CHEBI:34683
Physicochemical roles
- Role
- BUFFER
- Confidence
- 1.0
- Evidence
- Reference text
- CultureMech database (637 occurrences as 'Buffer')
- Reference type
- DATABASE_ENTRY
- Url
- https://github.com/CultureBotAI/CultureMech
- Excerpt
- Role: Buffer; Properties: Inorganic compound, Defined component, Simple component
- Curator note
- Widespread use in media formulations (637 occurrences). High confidence based on 'Defined component' property.
- Role
- BUFFER
- Confidence
- 0.6
- Evidence
- Reference type
- COMPUTATIONAL_PREDICTION
- Reference text
- Assigned by in-session Claude reasoning (no external API)
- Curator note
- Provisional in-session LLM role assignment; review recommended.
Synonyms (13)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| Role: Buffer; Properties: Defined component, Inorganic compound, Simple component | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Inorganic compound, Solution | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Simple component, Inorganic compound | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Solution, Inorganic compound | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Inorganic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| Dibasic sodium phosphate | EXACT | manual | |
| Disodium hydrogen phosphate | EXACT | manual | |
| Disodium Phosphate | EXACT_SYNONYM | kg_microbe | |
| Na HPO | EXACT_SYNONYM | kg_microbe | |
| Na HPO anydrous | EXACT_SYNONYM | kg_microbe | |
| Na2H2PO4 | EXACT_SYNONYM | kg_microbe | |
| Role: Buffer; Properties: Inorganic compound, Simple component, Defined component | RAW_TEXT | CultureMech | |
| Sodium phosphate dibasic | RAW_TEXT | semantic_review_merge |
Rejected enrichment labels (14)
Provenance-only candidates: these are not synonyms and do not resolve to this record.
| Rejected label | Disposition | Source | Occurrences |
|---|---|---|---|
| Na2HPO4 × 12 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x H2O | REJECTED_LABEL | merged_from_duplicate_mim_record | |
| Na2HPO4 . 12H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 12 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 2 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 2H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 3 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 6 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x 7 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4 x2 H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4.12H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4.7H2O | REJECTED_LABEL | kg_microbe | |
| Na2HPO4·12H2O | REJECTED_LABEL | kg_microbe | |
| Sodium dihydrogen phosphate | REJECTED_LABEL | sssom_other_backfill |
Chemical properties
- Cas rn
- 7558-79-4
- Data source
- CultureBotHT compounds_to_cas.csv
- Retrieval date
- 2026-04-05T21:48:45.466006+00:00
- Molecular formula
- HO4P.2Na
- Inchi
- InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
- Smiles
- O=P([O-])([O-])O.[Na+].[Na+]
Evidence (2)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
VSMCs were then cultured in 2.6 mM Na2HPO4 and 50 μg/mL ascorbic acid for 7 days to obtain a calcification model, and we investigated the effects and mechanisms of Cap on VSMCs calcification by assessing the changes of calcium deposition, calcium content, and subsequent VC biomarkers.
Auto-proposed; curator should rephrase or remove.
Occurrence statistics
- Total occurrences
- 1,157
- Distinct media
- 1,154
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:51:52.610803+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:7558-79-4 from PubChem API via name lookup (Disodium Phosphate) |
| 2026-04-05T21:48:45.002689+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:7558-79-4 from CultureBotHT compounds_to_cas.csv (matched: Disodium phosphate) |
| 2026-04-05T21:48:45.466011+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:7558-79-4 from CultureBotHT compounds_to_cas.csv (matched: Na2HPO4) |
| 2026-04-09T00:32:50.689620+00:00 | enrich_mim_cas_rn_batch | CAS_RN_ADDED | MAPPED | Added CAS-RN 7558-79-4 from PubChem (via CHEBI:34683) |
| 2026-04-17T12:00:00+00:00 | synonym_expansion_cbclaw LLM | ADDED_SYNONYMS | MAPPED | Added 2 synonyms for unmapped CultureMech surface forms |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 5 synonyms from kg-microbe P4.4 enrichment: Disodium Phosphate, Na HPO, Na HPO anydrous, Na2H2PO4, Na2HPO4 × 12 H2O |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 7 synonyms from kg-microbe P4.4 enrichment: Dibasic sodium phosphate, Disodium hydrogen phosphate, Na HPO, Na HPO anydrous, Na2H2PO4, ... (2 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 11 synonyms from kg-microbe P4.4 enrichment: Na2HPO4 . 12H2O, Na2HPO4 x 12 H2O, Na2HPO4 x 2 H2O, Na2HPO4 x 2H2O, Na2HPO4 x 3 H2O, ... (6 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 3 duplicate MIM record(s) into this one: Disodium_Phosphate.yaml, Na2hpo4_X_H2o.yaml, Disodium_Phosphate_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:35.154236+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:31.219638+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=HO4P.2Na; inchi=InChI=1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2; smiles=O=P([O-])([O-])O.[Na+].[Na+] | |
| 2026-05-01T08:09:47.984239+00:00 | auto_classify_ingredient_type | APPLY_EVIDENCE_PROPOSAL | added pmid=38524547 from propose-evidence batch | |
| 2026-05-02T03:12:16.956301+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-05-29T23:35:36.112135+00:00 | extract_roles_from_synonyms | ANNOTATED | Added media role: BUFFER (confidence: 1.00) | |
| 2026-06-09T05:23:46.806145+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'Na2HPO4' -> 'disodium hydrogenphosphate': synced to canonical CHEBI label (preferred_term 'Na2HPO4' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): BUFFER -> physicochemical_roles.BUFFER | |
| 2026-08-27T03:16:39.519459+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 77/637 -> 1121/1124 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-09-12T00:00:00+00:00 | fix_malformed_hydrate_identities | REJECTED_MALFORMED_HYDRATE_ALIASES | MAPPED | Marked malformed hydrate alias(es) as REJECTED_LABEL so they remain on their own #344 local identities only: 'Na2HPO4 x 3 H2O', 'Na2HPO4 x 6 H2O'. |
| 2026-09-12T00:00:00+00:00 | reject_hidden_hydrate_synonym_collapses | REJECTED_HIDDEN_HYDRATE_SYNONYMS | MAPPED | Marked hidden hydrate synonym(s) as REJECTED_LABEL so this record no longer resolves sibling hydrate identities (#251): 'Na2HPO4 × 12 H2O', 'Na2HPO4 x H2O', 'Na2HPO4 . 12H2O', 'Na2HPO4 x 12 H2O', 'Na2HPO4 x 2 H2O', 'Na2HPO4 x 2H2O', 'Na2HPO4 x 7 H2O', 'Na2HPO4 x2 H2O', 'Na2HPO4.12H2O', 'Na2HPO4.7H2O', 'Na2HPO4·12H2O'. |
| 2026-09-21T21:33:25.379198+00:00 | mim_semantic_review_20260921 LLM | MERGED_FROM_DUPLICATES | MAPPED | Absorbed Sodium_Phosphate_Dibasic. Dibasic sodium phosphate is disodium hydrogenphosphate, not trisodium phosphate. Sodium dihydrogen phosphate is monobasic and is a REJECTED_LABEL here; its 78 recipe rows are excluded from this transfer. Synonym dispositions and role evidence retained. Counts recomputed from distinct recipe membership where nonzero. Evidence: https://www.ebi.ac.uk/chebi/CHEBI:34683 |