Ontology mapping
- Primary identifier
-
CHEBI:32139 - Ontology label
- sodium hydrogencarbonate
- kg-microbe node
CHEBI:32139
Physicochemical roles
- Role
- BUFFER
- Confidence
- 1.0
- Evidence
- Reference text
- CultureMech database (2213 occurrences as 'Buffer')
- Reference type
- DATABASE_ENTRY
- Url
- https://github.com/CultureBotAI/CultureMech
- Excerpt
- Role: Buffer; Properties: Defined component, Inorganic compound, Simple component
- Curator note
- Widespread use in media formulations (2213 occurrences). High confidence based on 'Defined component' property.
Synonyms (26)
| Synonym | Type | Source | Occurrences |
|---|---|---|---|
| (5% w/v solution) | RAW_TEXT | CultureMech | |
| (after autoclaving) | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Inorganic compound, Simple component | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Inorganic compound, Solution | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Defined component, Simple component, Inorganic compound | RAW_TEXT | CultureMech | |
| E 500 | EXACT_SYNONYM | kg_microbe | |
| E-500 | EXACT_SYNONYM | kg_microbe | |
| E500 | EXACT_SYNONYM | kg_microbe | |
| NaHCO | EXACT_SYNONYM | kg_microbe | |
| Natriumhydrogenkarbonat | EXACT_SYNONYM | kg_microbe | |
| Sodium Bicarbonate | EXACT_SYNONYM | kg_microbe | |
| Sodium hydrogencarbonate | EXACT_SYNONYM | kg_microbe | |
| baking soda | EXACT_SYNONYM | kg_microbe | |
| bicarbonate of soda | EXACT_SYNONYM | kg_microbe | |
| carbonic acid monosodium salt | EXACT_SYNONYM | kg_microbe | |
| sodium acid carbonate | EXACT_SYNONYM | kg_microbe | |
| sodium hydrogen carbonate | EXACT_SYNONYM | kg_microbe | |
| Role: Buffer; Properties: Inorganic compound, Defined component, Simple component | RAW_TEXT | CultureMech | |
| Role: Buffer; Properties: Simple component, Defined component, Inorganic compound | RAW_TEXT | CultureMech | |
| NaHCO3(Fisher S 233) | RAW_TEXT | CultureMech | |
| NaHCO3 (10% (w/v)) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| NaHCO3 (10%, w/v) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| NaHCO3 (1 M) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| NaHCO3 (3% (w/v)) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| NaHCO3 (5%, w/v) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv | |
| NaHCO3 (7.5% w/v in water) | RAW_TEXT | culturemech:output/ingredient_occurrences.tsv |
Chemical properties
- Cas rn
- 144-55-8
- Data source
- PubChem API
- Retrieval date
- 2026-04-05T19:53:27.670613+00:00
- Molecular formula
- CHO3.Na
- Inchi
- InChI=1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
- Smiles
- O=C([O-])O.[Na+]
Evidence (2)
DATABASE_MATCH
via CultureMech
Imported from CultureMech pipeline, quality=DIRECT_MATCH
The GSH-activated Dox prodrug [Poly(lactic-co-glycolic acid)-disulfide-Dox, PLGA-ss-Dox], GA, and sulfur-terminated D-α-tocopherol polyethylene glycol succinate (TPGS-SH) are combined to form a nanoemulsion with sodium bicarbonate (NaHCO3) in the aqueous phase.
Auto-proposed; curator should rephrase or remove.
Occurrence statistics
- Total occurrences
- 3,168
- Distinct media
- 3,163
Curation history
| Timestamp | Curator | Action | New status | Changes |
|---|---|---|---|---|
| 2026-03-09T06:54:18.022301+00:00 | import_from_culturemech | IMPORTED | MAPPED | Initial import from CultureMech pipeline |
| 2026-04-05T19:53:27.670666+00:00 | fetch_cas_rn_from_pubchem | ADDED_CAS_RN | MAPPED | Added CAS-RN:144-55-8 from PubChem API via name lookup (NaHCO3) |
| 2026-04-05T21:48:45.731932+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:144-55-8 from CultureBotHT compounds_to_cas.csv (matched: Sodium bicarbonate) |
| 2026-04-05T21:48:45.733900+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:144-55-8 from CultureBotHT compounds_to_cas.csv (matched: sodium bicarbonate) |
| 2026-04-05T21:48:45.735926+00:00 | fetch_cas_rn_from_culturebot_csv | ADDED_CAS_RN | MAPPED | Added CAS-RN:144-55-8 from CultureBotHT compounds_to_cas.csv (matched: Sodium Bicarbonate) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 12 synonyms from kg-microbe P4.4 enrichment: E 500, E-500, E500, NaHCO, Natriumhydrogenkarbonat, ... (7 more) |
| 2026-04-18T00:00:00+00:00 | cbclaw_kg_microbe_sweep LLM | ADDED_SYNONYMS | MAPPED | Added 12 synonyms from kg-microbe P4.4 enrichment: E 500, E-500, E500, NaHCO, NaHCO3, ... (7 more) |
| 2026-04-19T07:39:23.955331+00:00 | audit_mim_merge | MERGED_FROM_DUPLICATES | MAPPED | Absorbed 3 duplicate MIM record(s) into this one: Sodium_Bicarbonate.yaml, Sodium_Bicarbonate_2.yaml, Sodium_Bicarbonate_3.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break. |
| 2026-05-01T07:35:35.381710+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (CHEBI primary) | |
| 2026-05-01T08:08:31.463410+00:00 | auto_classify_ingredient_type | AUTO_BACKFILL_CHEBI_CHEMISTRY | molecular_formula=CHO3.Na; inchi=InChI=1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1; smiles=O=C([O-])O.[Na+] | |
| 2026-05-01T08:09:48.033949+00:00 | auto_classify_ingredient_type | APPLY_EVIDENCE_PROPOSAL | added pmid=39954419 from propose-evidence batch | |
| 2026-05-02T03:12:17.222843+00:00 | auto_classify_ingredient_type | AUTO_CLASSIFY_INGREDIENT_TYPE | set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula)) | |
| 2026-05-06T00:00:00+00:00 | unmapped_ols_exact_audit | MERGED_FROM_UNMAPPED_DUPLICATE | MAPPED | Added source variant "NaHCO3(Fisher S 233)" and retired duplicate unmapped record Nahco.yaml after normalization to NaHCO3; occurrence counts were summed. |
| 2026-05-29T23:35:36.112331+00:00 | extract_roles_from_synonyms | ANNOTATED | Added media role: BUFFER (confidence: 1.00) | |
| 2026-06-09T05:23:46.809724+00:00 | correct_stale_ontology_labels.py | CORRECTED | ontology_label 'NaHCO3' -> 'sodium hydrogencarbonate': synced to canonical CHEBI label (preferred_term 'NaHCO3' unchanged). | |
| 2026-07-20T00:00:00+00:00 | migrate_media_roles_to_facets | ANNOTATED | Migrated legacy media_roles to role facets (#128): BUFFER -> physicochemical_roles.BUFFER | |
| 2026-08-27T03:16:39.519545+00:00 | refresh_occurrence_statistics | CORRECTED | occurrence_statistics 109/2213 -> 3163/3168 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257] | |
| 2026-08-30T04:48:06.233536+00:00 | claude_culturemech_alias_backfill | ADDED_SYNONYMS | Added 6 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'NaHCO3 (10% (w/v))' (x6 CultureMech mentions); 'NaHCO3 (10%, w/v)' (x5 CultureMech mentions); 'NaHCO3 (1 M)' (x1 CultureMech mentions); 'NaHCO3 (3% (w/v))' (x1 CultureMech mentions); 'NaHCO3 (5%, w/v)' (x1 CultureMech mentions); 'NaHCO3 (7.5% w/v in water)' (x1 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv. |