Nicotinamide

Ontology mapping

Primary identifier: CHEBI:17154
Ontology label: nicotinamide
kg-microbe node: CHEBI:17154

Nutritional roles

Role
VITAMIN_SOURCE
Confidence
0.7
Evidence
- Reference type
  COMPUTATIONAL_PREDICTION
  Reference text
  Inferred from CHEBI ancestry: subclass/has_role of CHEBI:33229 (vitamin (role))
  Curator note
  Provisional role inferred from CHEBI is_a/has_role closure; review recommended.

Synonyms (24)

Synonym	Type	Source
Cross-references: KEGG:ncam	RAW_TEXT	CultureMech
Role: Growth factor; Properties: Organic compound, Defined component, Simple component	RAW_TEXT	CultureMech
Role: Growth factor; Properties: Organic compound, Simple component, Defined component	RAW_TEXT	CultureMech
Nicotine amide	EXACT	manual
Niacinamide	EXACT	manual
3-carbamoylpyridine	EXACT_SYNONYM	kg_microbe
3-pyridinecarboxamide	EXACT_SYNONYM	kg_microbe
Nicotinamid	EXACT_SYNONYM	kg_microbe
Nicotinic acid amide	EXACT_SYNONYM	kg_microbe
Nicotinsaeureamid	EXACT_SYNONYM	kg_microbe
Nikotinamid	EXACT_SYNONYM	kg_microbe
Nikotinsaeureamid	EXACT_SYNONYM	kg_microbe
Vitamin PP	EXACT_SYNONYM	kg_microbe
beta-pyridinecarboxamide	EXACT_SYNONYM	kg_microbe
m-(aminocarbonyl)pyridine	EXACT_SYNONYM	kg_microbe
niamide	EXACT_SYNONYM	kg_microbe
nicotinamida	EXACT_SYNONYM	kg_microbe
nicotinamidum	EXACT_SYNONYM	kg_microbe
nicotine acid amide	EXACT_SYNONYM	kg_microbe
nicotinic amide	EXACT_SYNONYM	kg_microbe
nicotylamide	EXACT_SYNONYM	kg_microbe
pyridine-3-carboxamide	EXACT_SYNONYM	kg_microbe
pyridine-3-carboxylic acid amide	EXACT_SYNONYM	kg_microbe
Nicotinamide (Niacinamide)	RAW_TEXT	culturemech:output/ingredient_occurrences.tsv

Chemical properties

Cas rn: 98-92-0
Data source: CultureBotHT compounds_to_cas.csv
Retrieval date: 2026-04-05T21:48:45.594405+00:00
Molecular formula: C6H6N2O
Inchi: InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
Smiles: NC(=O)c1cccnc1

Evidence (1)

DATABASE_MATCH via CultureMech

Imported from CultureMech pipeline, quality=DIRECT_MATCH

Occurrence statistics

Total occurrences: 254
Distinct media: 254

Curation history

Timestamp	Curator	Action	New status	Changes
2026-03-09T06:54:18.022301+00:00	import_from_culturemech	IMPORTED	MAPPED	Initial import from CultureMech pipeline
2026-04-05T19:53:33.322635+00:00	fetch_cas_rn_from_pubchem	ADDED_CAS_RN	MAPPED	Added CAS-RN:98-92-0 from PubChem API via name lookup (Niacinamide)
2026-04-05T21:48:45.594410+00:00	fetch_cas_rn_from_culturebot_csv	ADDED_CAS_RN	MAPPED	Added CAS-RN:98-92-0 from CultureBotHT compounds_to_cas.csv (matched: Nicotinamide)
2026-04-05T21:48:45.596424+00:00	fetch_cas_rn_from_culturebot_csv	ADDED_CAS_RN	MAPPED	Added CAS-RN:98-92-0 from CultureBotHT compounds_to_cas.csv (matched: nicotinamide)
2026-04-09T00:32:50.689620+00:00	enrich_mim_cas_rn_batch	CAS_RN_ADDED	MAPPED	Added CAS-RN 98-92-0 from PubChem (via CHEBI:17154)
2026-04-17T12:00:00+00:00	synonym_expansion_cbclaw LLM	ADDED_SYNONYMS	MAPPED	Added 2 synonyms for unmapped CultureMech surface forms
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 18 synonyms from kg-microbe P4.4 enrichment: 3-carbamoylpyridine, 3-pyridinecarboxamide, Nicotinamid, Nicotinic acid amide, Nicotinsaeureamid, ... (13 more)
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 19 synonyms from kg-microbe P4.4 enrichment: 3-carbamoylpyridine, 3-pyridinecarboxamide, Niacinamide, Nicotinamid, Nicotinamide, ... (14 more)
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 18 synonyms from kg-microbe P4.4 enrichment: 3-carbamoylpyridine, 3-pyridinecarboxamide, Nicotinamid, Nicotinamide, Nicotinic acid amide, ... (13 more)
2026-04-18T00:00:00+00:00	cbclaw_kg_microbe_sweep LLM	ADDED_SYNONYMS	MAPPED	Added 19 synonyms from kg-microbe P4.4 enrichment: 3-carbamoylpyridine, 3-pyridinecarboxamide, Niacinamide, Nicotinamid, Nicotinic acid amide, ... (14 more)
2026-04-19T07:39:23.955331+00:00	audit_mim_merge	MERGED_FROM_DUPLICATES	MAPPED	Absorbed 3 duplicate MIM record(s) into this one: Nicotinic_Acid_Amide.yaml, Niacinamide.yaml, Nicotinamide_2.yaml. Synonyms, curation_history, and occurrence counts were unioned/summed; winner selected by highest occurrence count with preferred_term readability tie-break.
2026-05-01T07:35:35.549448+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (CHEBI primary)
2026-05-01T08:08:31.648257+00:00	auto_classify_ingredient_type	AUTO_BACKFILL_CHEBI_CHEMISTRY		molecular_formula=C6H6N2O; inchi=InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,; smiles=NC(=O)c1cccnc1
2026-05-02T03:12:17.429183+00:00	auto_classify_ingredient_type	AUTO_CLASSIFY_INGREDIENT_TYPE		set ingredient_type=SINGLE_INGREDIENT (chemical structure populated (molecular_formula))
2026-05-30T00:34:39.583133+00:00	infer_roles_from_chebi_ancestry	ANNOTATED		Added media role: VITAMIN_SOURCE (confidence: 0.70)
2026-06-09T05:23:46.812921+00:00	correct_stale_ontology_labels.py	CORRECTED		ontology_label 'Nicotinamide' -> 'nicotinamide': synced to canonical CHEBI label (preferred_term 'Nicotinamide' unchanged).
2026-07-20T00:00:00+00:00	migrate_media_roles_to_facets	ANNOTATED		Migrated legacy media_roles to role facets (#128): VITAMIN_SOURCE -> nutritional_roles.VITAMIN_SOURCE
2026-08-27T03:16:39.519623+00:00	refresh_occurrence_statistics	CORRECTED		occurrence_statistics 62/119 -> 254/254 (media_count/total_occurrences), derived from distinct CultureMech recipe ids in the #337 occurrence table. The prior values came from the importer retired in #453, whose media_count counted a list truncated to 50 examples (#449). [source=ingredient_occurrences.tsv culturemech_rev=15a4da5c08 rows=194137 distinct_recipes=15257]
2026-08-30T04:48:06.233536+00:00	claude_culturemech_alias_backfill	ADDED_SYNONYMS		Added 1 CultureMech recipe surface form(s) that folded onto this record's published label but were absent from MIM's label index, so CultureMech could not resolve them: 'Nicotinamide (Niacinamide)' (x1 CultureMech mentions). Source: culturemech:output/ingredient_occurrences.tsv.